Detailed information NTG0325882

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EGX72_RS07955
• Genome accession: NZ_CP033809
• Coordinates: 1501284..1503521 (-)
• Length: 745 a.a.
• NCBI ID: WP_000939903.1
• Uniprot ID: A0AAV3JP21
• Organism: Streptococcus sp. FDAARGOS_521
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1496284..1508521

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX72_RS07930 (EGX72_07925)	holA	1496348..1497385 (-)	1038	WP_000560292.1	DNA polymerase III subunit delta	-
EGX72_RS07935 (EGX72_07930)	-	1497439..1498167 (-)	729	WP_000468966.1	methyltransferase domain-containing protein	-
EGX72_RS07940 (EGX72_07935)	-	1498343..1499335 (+)	993	WP_000800998.1	alpha/beta hydrolase fold domain-containing protein	-
EGX72_RS07945 (EGX72_07940)	-	1499394..1500338 (-)	945	WP_000200830.1	LacI family DNA-binding transcriptional regulator	-
EGX72_RS07950 (EGX72_07945)	-	1500349..1501158 (-)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
EGX72_RS07955 (EGX72_07950)	comEC/celB	1501284..1503521 (-)	2238	WP_000939903.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EGX72_RS07960 (EGX72_07955)	-	1503505..1504158 (-)	654	WP_000461744.1	helix-hairpin-helix domain-containing protein	-
EGX72_RS07965 (EGX72_07960)	-	1504258..1504998 (-)	741	WP_000500220.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
EGX72_RS07970 (EGX72_07965)	-	1505133..1505897 (+)	765	WP_000567425.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EGX72_RS07975 (EGX72_07970)	-	1505890..1506156 (+)	267	WP_000598736.1	GIY-YIG nuclease family protein	-
EGX72_RS07980 (EGX72_07975)	-	1506341..1507927 (-)	1587	WP_000673090.1	DEAD/DEAH box helicase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85440.37 Da
• Isoelectric Point: 9.8459

>NTDB_id=325882 EGX72_RS07955 WP_000939903.1 1501284..1503521(-) (comEC/celB) [Streptococcus sp. FDAARGOS_521]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFSFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFALMSKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLSCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAKRTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKHLSKIGVAVKSIEAGDKLAVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=325882 EGX72_RS07955 WP_000939903.1 1501284..1503521(-) (comEC/celB) [Streptococcus sp. FDAARGOS_521]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTTCTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGCTCTTATGTCTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCCCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAAGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTGTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAGGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTAATGCTA
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATGATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCATTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAACTTGCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTTTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-458)

• Domain of unknown function (DUF4131) (DUF4131) (27-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.4	100	0.487
comEC/celB	Streptococcus mitis SK321	48.529	100	0.487
comEC/celB	Streptococcus pneumoniae TIGR4	47.059	100	0.472
comEC/celB	Streptococcus pneumoniae Rx1	46.586	100	0.467
comEC/celB	Streptococcus pneumoniae D39	46.586	100	0.467
comEC/celB	Streptococcus pneumoniae R6	46.586	100	0.467
comEC	Lactococcus lactis subsp. cremoris KW2	43.338	99.732	0.432