Detailed information NTG0325856

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: FNL90_RS02190
• Genome accession: NZ_CP041408
• Coordinates: 412922..415075 (-)
• Length: 717 a.a.
• NCBI ID: WP_047235192.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 37-97S
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 407922..420075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FNL90_RS02170 (FNL90_02245)	comE/blpR	409112..409861 (+)	750	WP_002992578.1	response regulator transcription factor	Regulator
FNL90_RS02175 (FNL90_02250)	-	409862..411196 (+)	1335	WP_047235191.1	sensor histidine kinase	-
FNL90_RS09890 (FNL90_02255)	-	411344..411463 (-)	120	WP_185168158.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
FNL90_RS02185 (FNL90_02260)	-	411547..412911 (-)	1365	WP_014635340.1	bacteriocin secretion accessory protein	-
FNL90_RS02190 (FNL90_02265)	comA/nlmT	412922..415075 (-)	2154	WP_047235192.1	peptide cleavage/export ABC transporter	Regulator
FNL90_RS02195 (FNL90_02275)	-	415528..416214 (+)	687	Protein_383	transposase	-
FNL90_RS02200 (FNL90_02280)	-	416402..416659 (+)	258	WP_023078219.1	Blp family class II bacteriocin	-
FNL90_RS02205 (FNL90_02285)	-	416674..416856 (+)	183	WP_002987564.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
FNL90_RS02210 (FNL90_02290)	-	417047..417733 (-)	687	Protein_386	transposase	-
FNL90_RS02215 (FNL90_02295)	-	418053..418280 (+)	228	WP_002992018.1	Blp family class II bacteriocin	-
FNL90_RS02220 (FNL90_02300)	-	418293..418493 (+)	201	WP_002985729.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
FNL90_RS09720 (FNL90_02310)	-	418855..418983 (+)	129	WP_002985724.1	hypothetical protein	-
FNL90_RS02225 (FNL90_02320)	-	419509..419910 (+)	402	WP_047235194.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80542.47 Da
• Isoelectric Point: 7.1728

>NTDB_id=325856 FNL90_RS02190 WP_047235192.1 412922..415075(-) (comA/nlmT) [Streptococcus pyogenes strain 37-97S]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPNPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLINFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIETGSHQELMTKQGFYHHLFSG

Nucleotide

• Length: 2154 bp

>NTDB_id=325856 FNL90_RS02190 WP_047235192.1 412922..415075(-) (comA/nlmT) [Streptococcus pyogenes strain 37-97S]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGGTTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTAACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAACTTTTTACCTCTT
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAC
GTCATTTTATCTTACATTCGCCATATTTTTGAATTACCCATGTCTTTTTTTGCAACTCGCAGAACAGGAGAAATCATTTC
ACGGTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACCAAACTTCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAATTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCGCTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAACAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTGGTTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.867	99.721	0.727
comA	Streptococcus mitis NCTC 12261	67.511	99.163	0.669
comA	Streptococcus pneumoniae Rx1	67.089	99.163	0.665
comA	Streptococcus pneumoniae D39	67.089	99.163	0.665
comA	Streptococcus pneumoniae R6	67.089	99.163	0.665
comA	Streptococcus mitis SK321	67.089	99.163	0.665
comA	Streptococcus pneumoniae TIGR4	66.807	99.163	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	66.014	99.721	0.658