Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EGX70_RS10670 Genome accession   NZ_CP033808
Coordinates   2035918..2036607 (+) Length   229 a.a.
NCBI ID   WP_123948131.1    Uniprot ID   -
Organism   Streptococcus sp. FDAARGOS_522     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2030918..2041607
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX70_RS10645 (EGX70_10640) - 2031345..2032724 (-) 1380 WP_000680112.1 TrkH family potassium uptake protein -
  EGX70_RS10650 (EGX70_10645) rsmG 2032739..2033452 (-) 714 WP_000188792.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EGX70_RS10655 (EGX70_10650) - 2033580..2034134 (+) 555 WP_000537055.1 LemA family protein -
  EGX70_RS10660 (EGX70_10655) htpX 2034155..2035045 (+) 891 WP_000966817.1 zinc metalloprotease HtpX -
  EGX70_RS10665 (EGX70_10660) - 2035150..2035683 (+) 534 WP_000927543.1 DUF177 domain-containing protein -
  EGX70_RS10670 (EGX70_10665) covR 2035918..2036607 (+) 690 WP_123948131.1 response regulator transcription factor Regulator
  EGX70_RS10675 (EGX70_10670) - 2036597..2038102 (+) 1506 WP_000791112.1 HAMP domain-containing histidine kinase -
  EGX70_RS10680 (EGX70_10675) nrdR 2038251..2038730 (+) 480 WP_001203682.1 transcriptional regulator NrdR -
  EGX70_RS10685 (EGX70_10680) - 2038730..2039905 (+) 1176 WP_000074512.1 DnaD domain protein -
  EGX70_RS10690 (EGX70_10685) dnaI 2039902..2040804 (+) 903 WP_000843626.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26475.49 Da        Isoelectric Point: 4.8849

>NTDB_id=325856 EGX70_RS10670 WP_123948131.1 2035918..2036607(+) (covR) [Streptococcus sp. FDAARGOS_522]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKGKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=325856 EGX70_RS10670 WP_123948131.1 2035918..2036607(+) (covR) [Streptococcus sp. FDAARGOS_522]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGGAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.789

99.563

0.655
  vicR Streptococcus mutans UA159

45.455

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment