Detailed information NTG0325514

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EGX78_RS05240
• Genome accession: NZ_CP033767
• Coordinates: 986980..987816 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain FDAARGOS_534
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 981980..992816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX78_RS05210 (EGX78_05215)	-	982462..982902 (+)	441	WP_024623381.1	hypothetical protein	-
EGX78_RS05215 (EGX78_05220)	-	982952..983863 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
EGX78_RS05220 (EGX78_05225)	-	983980..984630 (-)	651	WP_002984629.1	hemolysin III family protein	-
EGX78_RS05225 (EGX78_05230)	-	984627..985067 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
EGX78_RS05230 (EGX78_05235)	ylqF	985286..986134 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
EGX78_RS05235 (EGX78_05240)	-	986124..986915 (+)	792	WP_002989771.1	ribonuclease HII	-
EGX78_RS05240 (EGX78_05245)	dprA	986980..987816 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
EGX78_RS05245 (EGX78_05250)	topA	987923..990052 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
EGX78_RS09470	-	990127..990984 (-)	858	Protein_961	LysR family transcriptional regulator	-
EGX78_RS05260 (EGX78_05265)	-	991024..991590 (+)	567	Protein_962	PTS sugar transporter subunit IIC	-
EGX78_RS05265 (EGX78_05270)	-	991605..992597 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=325514 EGX78_RS05240 WP_002989770.1 986980..987816(+) (dprA) [Streptococcus pyogenes strain FDAARGOS_534]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=325514 EGX78_RS05240 WP_002989770.1 986980..987816(+) (dprA) [Streptococcus pyogenes strain FDAARGOS_534]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367