Detailed information NTG0325503

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FMA85_RS12195
• Genome accession: NZ_CP041337
• Coordinates: 2457491..2458765 (-)
• Length: 424 a.a.
• NCBI ID: WP_000130299.1
• Uniprot ID: -
• Organism: Escherichia coli strain CCUG 73778
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2452491..2463765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FMA85_RS12185 (FMA85_12475)	hupB	2454468..2454758 (-)	291	WP_254892905.1	nucleoid-associated protein HU-beta	-
FMA85_RS12190 (FMA85_12480)	lon	2454949..2457303 (-)	2355	WP_001295325.1	endopeptidase La	-
FMA85_RS12195 (FMA85_12485)	clpX	2457491..2458765 (-)	1275	WP_000130299.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
FMA85_RS12200 (FMA85_12490)	clpP	2458891..2459514 (-)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
FMA85_RS12205 (FMA85_12495)	tig	2459760..2461058 (-)	1299	WP_001198388.1	trigger factor	-
FMA85_RS12210 (FMA85_12500)	bolA	2461402..2461719 (-)	318	WP_000973448.1	transcriptional regulator BolA	-
FMA85_RS12215 (FMA85_12505)	yajG	2462024..2462602 (+)	579	WP_001295326.1	lipoprotein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46316.97 Da
• Isoelectric Point: 4.9297

>NTDB_id=325503 FMA85_RS12195 WP_000130299.1 2457491..2458765(-) (clpX) [Escherichia coli strain CCUG 73778]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=325503 FMA85_RS12195 WP_000130299.1 2457491..2458765(-) (clpX) [Escherichia coli strain CCUG 73778]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGT
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCACTACAAACGTCTGCGCAACGGAGATACCAGCAATGG
CGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCCGAAACGCTGGCGC
GCCTGCTGGACGTTCCGTTCACCATGGCTGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTAAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCGCCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTCATCTGTGGCGGCGCATTTGCTGGCCTGGATAAAGTGATTGCCAATCGTGTTGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTGAAAGCCAAGTCCGACAAAGCCAGCGAAGGTGAACTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTGATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGATGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533