Detailed information NTG0325491

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: EGX78_RS00825
• Genome accession: NZ_CP033767
• Coordinates: 132209..132643 (+)
• Length: 144 a.a.
• NCBI ID: WP_002987783.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain FDAARGOS_534
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 127209..137643

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX78_RS00795 (EGX78_00795)	-	128878..129243 (+)	366	WP_002986560.1	DUF1033 family protein	-
EGX78_RS00800 (EGX78_00800)	comYA	129336..130274 (+)	939	WP_002987773.1	competence type IV pilus ATPase ComGA	Machinery gene
EGX78_RS00805 (EGX78_00805)	comYB	130210..131244 (+)	1035	WP_223845212.1	competence type IV pilus assembly protein ComGB	Machinery gene
EGX78_RS00810 (EGX78_00810)	comYC	131246..131572 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
EGX78_RS00815 (EGX78_00815)	comGD	131547..131975 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
EGX78_RS00820 (EGX78_00820)	comGE	131932..132216 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
EGX78_RS00825 (EGX78_00825)	comYF	132209..132643 (+)	435	WP_002987783.1	competence type IV pilus minor pilin ComGF	Machinery gene
EGX78_RS00830 (EGX78_00830)	comGG	132627..132953 (+)	327	WP_002987787.1	competence type IV pilus minor pilin ComGG	-
EGX78_RS00835 (EGX78_00835)	comYH	133051..134004 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
EGX78_RS00840 (EGX78_00840)	-	134063..135259 (+)	1197	WP_123949427.1	acetate kinase	-
EGX78_RS00845 (EGX78_00845)	-	135446..135754 (+)	309	WP_032461811.1	hypothetical protein	-
EGX78_RS00850 (EGX78_00850)	proC	135837..136607 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16585.23 Da
• Isoelectric Point: 10.2064

>NTDB_id=325491 EGX78_RS00825 WP_002987783.1 132209..132643(+) (comYF) [Streptococcus pyogenes strain FDAARGOS_534]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=325491 EGX78_RS00825 WP_002987783.1 132209..132643(+) (comYF) [Streptococcus pyogenes strain FDAARGOS_534]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396