Detailed information NTG0032433

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SMUNN2025_RS07000
• Genome accession: NC_013928
• Coordinates: 1437707..1439941 (-)
• Length: 744 a.a.
• NCBI ID: WP_002292457.1
• Uniprot ID: -
• Organism: Streptococcus mutans NN2025
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1432707..1444941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS06975 (SmuNN2025_1358)	sodA	1433490..1434101 (-)	612	WP_041160327.1	superoxide dismutase SodA	-
SMUNN2025_RS06980 (SmuNN2025_1359)	holA	1434248..1435288 (-)	1041	WP_002281296.1	DNA polymerase III subunit delta	-
SMUNN2025_RS06995 (SmuNN2025_1362)	-	1436895..1437521 (-)	627	WP_002292456.1	DUF805 domain-containing protein	-
SMUNN2025_RS07000 (SmuNN2025_1363)	comEC/celB	1437707..1439941 (-)	2235	WP_002292457.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SMUNN2025_RS07005 (SmuNN2025_1364)	comEA/celA/cilE	1439931..1440611 (-)	681	WP_012997873.1	helix-hairpin-helix domain-containing protein	Machinery gene
SMUNN2025_RS07010 (SmuNN2025_1365)	-	1440750..1441502 (-)	753	WP_002264733.1	lysophospholipid acyltransferase family protein	-
SMUNN2025_RS07015 (SmuNN2025_1366)	-	1441641..1442576 (+)	936	WP_012997875.1	polysaccharide deacetylase family protein	-
SMUNN2025_RS07020 (SmuNN2025_1367)	-	1442665..1443177 (+)	513	WP_002265382.1	HXXEE domain-containing protein	-
SMUNN2025_RS07025 (SmuNN2025_1368)	-	1443223..1444242 (+)	1020	WP_002280666.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85585.95 Da
• Isoelectric Point: 10.0565

>NTDB_id=32433 SMUNN2025_RS07000 WP_002292457.1 1437707..1439941(-) (comEC/celB) [Streptococcus mutans NN2025]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTFLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIISDTLSINGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQSNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSLLKRILFQTFSLSLGILPLLMWYFSSFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSSILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISSKTILIDVGGKVTFGQTDKWRQRISDTNAEKTLIPYLKSRGIDKIDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLQVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKNNRYKHPHQETLDRFAQIKSR
IYRTDQEGAIRFKGLKHWQIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=32433 SMUNN2025_RS07000 WP_002292457.1 1437707..1439941(-) (comEC/celB) [Streptococcus mutans NN2025]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGCTTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CATTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTTCAGATACGCTTAGTATCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCAGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTCACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTACCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAAGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACTCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAGTT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGTCGTCCTTTTATTTTGGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAGAAAAGGGTAGTGTTAGTACTTAGTAGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAGTAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTAACTTTTGGACAGACTGATAAATGGCGGCAGCGTATCAGTGATACTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGATTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACAGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAACAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTGCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (214-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

• Domain of unknown function (DUF4131) (DUF4131) (31-174)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	50.809	99.731	0.507
comEC/celB	Streptococcus mitis SK321	50.877	99.597	0.507
comEC/celB	Streptococcus pneumoniae TIGR4	50.403	100	0.504
comEC/celB	Streptococcus pneumoniae Rx1	49.731	100	0.497
comEC/celB	Streptococcus pneumoniae D39	49.731	100	0.497
comEC/celB	Streptococcus pneumoniae R6	49.731	100	0.497
comEC	Lactococcus lactis subsp. cremoris KW2	46.309	100	0.464