Detailed information NTG0324049

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: EEB07_RS07200
• Genome accession: NZ_CP033576
• Coordinates: 1371829..1372992 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain NY12-2
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1366829..1377992

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EEB07_RS07170 (EEB07_07170)	-	1367094..1367513 (-)	420	WP_061861586.1	TIGR03826 family flagellar region protein	-
EEB07_RS07175 (EEB07_07175)	comFC	1367587..1368276 (-)	690	WP_199803302.1	phosphoribosyltransferase family protein	Machinery gene
EEB07_RS07180 (EEB07_07180)	-	1368282..1368566 (-)	285	WP_003151389.1	competence protein ComFB	-
EEB07_RS07185 (EEB07_07185)	comFA	1368624..1370009 (-)	1386	WP_123117468.1	DEAD/DEAH box helicase	Machinery gene
EEB07_RS07190 (EEB07_07190)	-	1370117..1370965 (-)	849	WP_003151387.1	DegV family protein	-
EEB07_RS07195 (EEB07_07195)	degU	1371063..1371752 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
EEB07_RS07200 (EEB07_07200)	degS	1371829..1372992 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
EEB07_RS07205 (EEB07_07205)	-	1373215..1373862 (+)	648	WP_007614107.1	YigZ family protein	-
EEB07_RS07210 (EEB07_07210)	-	1373867..1375081 (+)	1215	WP_123117469.1	LCP family protein	-
EEB07_RS07215 (EEB07_07215)	-	1375180..1376256 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
EEB07_RS07220 (EEB07_07220)	-	1376388..1377584 (-)	1197	WP_123117470.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=324049 EEB07_RS07200 WP_007407484.1 1371829..1372992(-) (degS) [Bacillus velezensis strain NY12-2]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=324049 EEB07_RS07200 WP_007407484.1 1371829..1372992(-) (degS) [Bacillus velezensis strain NY12-2]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGCCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGATAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951