Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   LLKF_RS02275 Genome accession   NC_013656
Coordinates   445922..447364 (-) Length   480 a.a.
NCBI ID   WP_012897229.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis KF147     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 440922..452364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLKF_RS02250 (LLKF_0443) nox 440952..442292 (+) 1341 WP_012897225.1 H2O-forming NADH oxidase -
  LLKF_RS02255 (LLKF_0444) - 442383..442772 (+) 390 WP_012897226.1 single-stranded DNA-binding protein -
  LLKF_RS02260 (LLKF_0445) groES 442892..443176 (+) 285 WP_003131589.1 co-chaperone GroES -
  LLKF_RS02265 (LLKF_0446) groL 443264..444892 (+) 1629 WP_012897227.1 chaperonin GroEL -
  LLKF_RS02270 (LLKF_0447) vicX 444939..445751 (-) 813 WP_012897228.1 MBL fold metallo-hydrolase Regulator
  LLKF_RS02275 (LLKF_0448) vicK 445922..447364 (-) 1443 WP_012897229.1 sensor histidine kinase Regulator
  LLKF_RS02280 (LLKF_0449) yycF 447357..448058 (-) 702 WP_003131580.1 response regulator YycF -
  LLKF_RS02285 (LLKF_0450) tmk 448236..448871 (+) 636 WP_012897230.1 dTMP kinase -
  LLKF_RS02290 (LLKF_0451) - 449004..449864 (+) 861 WP_012897231.1 DNA polymerase III subunit delta' -
  LLKF_RS02295 (LLKF_0452) yaaT 449916..450698 (+) 783 WP_012897232.1 PSP1 domain-containing protein Regulator
  LLKF_RS02300 (LLKF_0453) yabA 450691..451017 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  LLKF_RS02305 (LLKF_0454) rsmI 451017..451892 (+) 876 WP_012897233.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  LLKF_RS02310 (LLKF_0455) - 451969..452160 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54649.12 Da        Isoelectric Point: 4.5889

>NTDB_id=32057 LLKF_RS02275 WP_012897229.1 445922..447364(-) (vicK) [Lactococcus lactis subsp. lactis KF147]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=32057 LLKF_RS02275 WP_012897229.1 445922..447364(-) (vicK) [Lactococcus lactis subsp. lactis KF147]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGACGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGAACAGGTTTAGGACTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGCACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442

Multiple sequence alignment