Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FD746_RS10135 Genome accession   NZ_CP040232
Coordinates   2026163..2026786 (-) Length   207 a.a.
NCBI ID   WP_001045136.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GD1706     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2021163..2031786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD746_RS10105 (FD746_10135) - 2021496..2022692 (-) 1197 WP_000238216.1 exonuclease SbcCD subunit D -
  FD746_RS10110 (FD746_10140) - 2022989..2023087 (-) 99 WP_002869660.1 hypothetical protein -
  FD746_RS10120 (FD746_10150) - 2023625..2023969 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  FD746_RS10125 (FD746_10155) - 2024038..2025162 (-) 1125 WP_000992534.1 DUF445 domain-containing protein -
  FD746_RS10130 (FD746_10160) - 2025341..2025805 (-) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  FD746_RS10135 (FD746_10165) vraR 2026163..2026786 (-) 624 WP_001045136.1 response regulator transcription factor Regulator
  FD746_RS10140 (FD746_10170) - 2026808..2027920 (-) 1113 WP_000437967.1 GAF domain-containing sensor histidine kinase -
  FD746_RS10145 (FD746_10175) - 2028083..2028904 (+) 822 WP_000669380.1 RluA family pseudouridine synthase -
  FD746_RS10150 (FD746_10180) fumC 2029359..2030744 (-) 1386 WP_000116238.1 class II fumarate hydratase -
  FD746_RS10155 (FD746_10185) - 2030940..2031335 (-) 396 WP_000901018.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23917.61 Da        Isoelectric Point: 5.9853

>NTDB_id=320517 FD746_RS10135 WP_001045136.1 2026163..2026786(-) (vraR) [Staphylococcus aureus strain GD1706]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPHIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=320517 FD746_RS10135 WP_001045136.1 2026163..2026786(-) (vraR) [Staphylococcus aureus strain GD1706]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TGGATTTAGTAATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGCATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362