Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   E6P00_RS12450 Genome accession   NZ_CP040127
Coordinates   2077711..2079723 (+) Length   670 a.a.
NCBI ID   WP_003104590.1    Uniprot ID   P72174
Organism   Pseudomonas aeruginosa strain PA298     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2072711..2084723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E6P00_RS12430 (E6P00_12430) - 2073592..2075589 (+) 1998 WP_003119734.1 nucleoside-diphosphate sugar epimerase/dehydratase -
  E6P00_RS12435 (E6P00_12435) comEA/comE1 2075780..2076109 (+) 330 WP_003104586.1 ComEA family DNA-binding protein Machinery gene
  E6P00_RS12445 (E6P00_12445) - 2076327..2077523 (-) 1197 WP_003104588.1 amino acid aminotransferase -
  E6P00_RS12450 (E6P00_12450) uvrB 2077711..2079723 (+) 2013 WP_003104590.1 excinuclease ABC subunit UvrB Machinery gene
  E6P00_RS12455 (E6P00_12455) - 2079727..2081226 (-) 1500 WP_137461903.1 MDR family MFS transporter -
  E6P00_RS12460 (E6P00_12460) - 2081276..2082310 (-) 1035 WP_003104593.1 HlyD family secretion protein -
  E6P00_RS12465 (E6P00_12465) - 2082413..2083333 (+) 921 WP_003091419.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 670 a.a.        Molecular weight: 76067.31 Da        Isoelectric Point: 5.0950

>NTDB_id=320106 E6P00_RS12450 WP_003104590.1 2077711..2079723(+) (uvrB) [Pseudomonas aeruginosa strain PA298]
MDTFQLDSRFKPAGDQPEAIRQMVEGLEAGLSHQTLLGVTGSGKTFSIANVIAQVQRPTLVLAPNKTLAAQLYGEFKTFF
PHNSVEYFVSYYDYYQPEAYVPSSDTYIEKDSSINDHIEQMRLSATKALLERPDAIIVATVSSIYGLGDPASYLKMVLHL
DRGDRIDQRELLRRLTSLQYTRNDMDFARATFRVRGDVIDIFPAESDLEAIRVELFDDEVESLSAFDPLTGEVIRKLPRF
TFYPKSHYVTPRETLLEAVDQIKAELKERLDYLRNNNKLVEAQRLEQRTRFDLEMILELGYCNGIENYSRYLSGRAPGEP
PPTLYDYLPANSLLVIDESHVSVPQVGAMFKGDRSRKETLVEYGFRLPSALDNRPLRFEEWEAVSPQTIFVSATPGPYEA
EHAGRVIEQVVRPTGLVDPEIEVRPAMTQVDDLLSQIRQRVAKDERVLVTTLTKRMAEDLTDYLGDHDVRVRYLHSDIDT
VERVEIIRDLRAGAFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLHGKAILYADNVTGSMQ
RAIDETERRRAKQIAFNEAHGIVPKGVRKDIKDILEGAVVPGARGKRKGVAKVAEESGRYENELRSPSEISKRIRQLEEK
MYQLARDLEFEAAAQLRDEIQTLRERLVNV

Nucleotide


Download         Length: 2013 bp        

>NTDB_id=320106 E6P00_RS12450 WP_003104590.1 2077711..2079723(+) (uvrB) [Pseudomonas aeruginosa strain PA298]
ATGGATACGTTCCAACTCGACTCGCGCTTCAAGCCCGCCGGCGACCAGCCGGAAGCCATCCGGCAGATGGTCGAGGGGCT
GGAGGCGGGGCTTTCGCACCAGACCCTGCTGGGGGTGACGGGCTCTGGCAAGACTTTCAGCATCGCCAACGTGATTGCCC
AGGTGCAGCGCCCGACCCTGGTCCTGGCGCCGAACAAGACCCTGGCGGCCCAGCTCTACGGGGAGTTCAAGACGTTCTTC
CCGCACAATTCCGTGGAGTACTTCGTTTCCTACTACGACTACTACCAGCCGGAGGCCTACGTCCCGTCTTCCGATACCTA
TATCGAGAAGGACTCCTCGATCAACGACCATATCGAGCAGATGCGCCTGTCGGCGACCAAGGCGCTGCTCGAGCGTCCGG
ATGCGATCATCGTCGCCACCGTGTCGTCCATCTACGGCCTCGGTGATCCCGCGTCCTACCTGAAGATGGTCCTGCACCTG
GACCGCGGCGACCGCATCGACCAGCGCGAACTGCTGCGGCGACTGACCAGCCTGCAGTACACCCGCAACGACATGGATTT
CGCCCGTGCGACTTTCCGTGTGCGTGGCGATGTGATCGACATCTTCCCGGCCGAATCCGATCTCGAGGCGATTCGTGTCG
AGTTGTTCGACGACGAGGTGGAAAGCCTCTCGGCCTTCGATCCGCTCACCGGCGAGGTGATCCGCAAGCTGCCGCGCTTC
ACCTTCTACCCCAAGAGCCACTACGTGACCCCGCGCGAGACGCTGCTGGAGGCGGTCGACCAGATCAAGGCCGAACTCAA
GGAACGCCTGGACTACCTGCGCAACAACAACAAGCTGGTGGAAGCGCAGCGCCTGGAGCAGCGCACCCGTTTCGACCTGG
AGATGATCCTCGAGCTGGGCTACTGCAACGGCATCGAGAACTACTCGCGCTATCTTTCCGGGCGGGCCCCCGGCGAGCCG
CCGCCGACGCTCTACGACTACCTGCCGGCCAACTCGCTGCTGGTTATCGACGAATCGCACGTCAGCGTTCCGCAGGTCGG
TGCGATGTTCAAGGGCGACCGCTCGCGCAAGGAGACCCTGGTGGAATACGGTTTCCGCCTGCCTTCGGCGCTGGACAACC
GGCCGCTGCGCTTCGAAGAGTGGGAGGCGGTGAGTCCGCAGACCATCTTCGTCTCCGCCACCCCGGGCCCCTACGAGGCG
GAGCATGCCGGGCGGGTCATCGAGCAGGTGGTGCGTCCCACCGGGCTGGTCGATCCGGAGATCGAGGTACGTCCGGCGAT
GACCCAGGTGGACGACCTGCTCTCGCAGATCCGCCAGCGTGTGGCCAAGGACGAGCGGGTGCTGGTGACTACCCTGACCA
AGCGCATGGCCGAGGACCTCACCGATTATCTCGGCGATCACGACGTGCGGGTGCGCTACTTGCACTCGGACATCGATACC
GTCGAGCGAGTGGAGATCATCCGCGACCTGCGCGCCGGTGCGTTCGACGTGCTGGTGGGGATCAACCTGCTGCGCGAAGG
CCTGGACATGCCCGAGGTGTCGCTGGTGGCGATCCTCGACGCGGACAAGGAAGGCTTCCTGCGCTCGGAGCGCTCGCTGA
TCCAGACCATCGGTCGTGCCGCGCGCAACCTGCACGGCAAGGCGATCCTCTACGCCGACAACGTCACCGGCTCGATGCAG
CGTGCGATCGACGAGACCGAGCGGCGTCGGGCCAAGCAGATCGCCTTCAACGAAGCCCATGGCATCGTGCCCAAGGGGGT
GCGCAAGGACATCAAGGACATTCTCGAAGGCGCCGTGGTGCCCGGCGCGCGCGGCAAGCGCAAGGGCGTGGCCAAGGTGG
CGGAGGAGAGCGGGCGCTACGAGAACGAACTGCGCTCGCCGAGCGAGATCAGCAAGCGCATCCGCCAACTGGAGGAAAAG
ATGTACCAGTTGGCCCGCGATCTGGAGTTCGAGGCGGCGGCGCAACTGCGCGACGAGATCCAGACGCTGCGCGAGCGCCT
GGTCAACGTCTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(632-665)

UvrB interaction domain (UvrB_inter)

(158-248)

Ultra-violet resistance protein B (UvrB)

(550-592)

Helicase conserved C-terminal domain (Helicase_C)

(435-542)

Type III restriction enzyme, res subunit (ResIII)

(11-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P72174

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.839

98.06

0.567
  uvrB Streptococcus pneumoniae R6

57.839

98.06

0.567
  uvrB Streptococcus pneumoniae D39

57.839

98.06

0.567

Multiple sequence alignment