Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FDQ49_RS13160 Genome accession   NZ_CP040105
Coordinates   2768534..2769208 (+) Length   224 a.a.
NCBI ID   WP_002051287.1    Uniprot ID   A0AA36K948
Organism   Acinetobacter nosocomialis M2     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2763534..2774208
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDQ49_RS13145 (FDQ49_13145) - 2763586..2764833 (+) 1248 WP_022575730.1 MFS transporter -
  FDQ49_RS13150 (FDQ49_13150) - 2765375..2766682 (+) 1308 WP_016805257.1 DcaP family trimeric outer membrane transporter -
  FDQ49_RS13155 (FDQ49_13155) - 2766870..2768519 (+) 1650 WP_022575731.1 phosphoethanolamine transferase -
  FDQ49_RS13160 (FDQ49_13160) ciaR 2768534..2769208 (+) 675 WP_002051287.1 DNA-binding response regulator PmrA Regulator
  FDQ49_RS13165 (FDQ49_13165) - 2769234..2770568 (+) 1335 WP_031225266.1 two-component system sensor histidine kinase PmrB -
  FDQ49_RS13170 (FDQ49_13170) - 2770565..2771263 (-) 699 WP_022575733.1 phosphatase PAP2 family protein -
  FDQ49_RS13175 (FDQ49_13175) - 2771523..2772710 (-) 1188 WP_031225268.1 ammonium transporter -
  FDQ49_RS13185 (FDQ49_13185) - 2773016..2773900 (-) 885 WP_004885457.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25535.39 Da        Isoelectric Point: 5.3246

>NTDB_id=319992 FDQ49_RS13160 WP_002051287.1 2768534..2769208(+) (ciaR) [Acinetobacter nosocomialis M2]
MTKILMIEDDFMIAESTTTLLQYHQFEVEWVNNGLDGLAQLAKNKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMSHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=319992 FDQ49_RS13160 WP_002051287.1 2768534..2769208(+) (ciaR) [Acinetobacter nosocomialis M2]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACAACGACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCCCAATTAGCAAAGAATAAGTTTGATCTCATTCTTTTAGACTTGG
GATTGCCAATGATGGATGGTATGCAAGTTTTAAAGCAGATCCGTCAAAGAGCAGCAACACCAGTCTTGATTATCTCTGCA
CGTGACCAACTGCAAAACCGTGTTGATGGTTTGAATTTGGGAGCAGATGATTACTTAATTAAGCCTTATGAGTTTGATGA
ATTACTCGCTCGTATTCATGCCTTATTACGCCGTAGTGGCGTAGAGGCTCAACTTGCAAGCCAAGATCAACTACTAGAAA
GCGGTGATCTGGTTTTAAATGTTGAACAGCACATTGCAACATTTAAAGGGCAACGTATTGATTTATCGAATCGTGAATGG
GCAATCTTGATTCCGCTTATGAGTCATCCAAATAAAATTTTCTCAAAAGCTAATTTGGAAGATAAGTTATATGACTTTGA
TAGTGATGTGACCAGCAACACAATTGAGGTATATGTCCATCATTTAAGGGCTAAGTTGGGTAAAGACTTTATTCGAACTA
TCCGAGGACTGGGTTACCGTTTAGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AA36K948

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

36.404

100

0.371