Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EA667_RS03715 Genome accession   NZ_CP039930
Coordinates   744153..744827 (+) Length   224 a.a.
NCBI ID   WP_000161505.1    Uniprot ID   A0A0D5YFC9
Organism   Acinetobacter baumannii strain TG29392     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 739153..749827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EA667_RS03690 (EA667_003690) - 739990..740175 (+) 186 Protein_692 lipid A phosphoethanolamine transferase -
  EA667_RS03695 (EA667_003695) - 740206..741789 (-) 1584 WP_001094410.1 IS66-like element ISAba25 family transposase -
  EA667_RS03700 (EA667_003700) tnpB 741864..742199 (-) 336 WP_000618092.1 IS66 family insertion sequence element accessory protein TnpB -
  EA667_RS03705 (EA667_003705) - 742196..742579 (-) 384 WP_001055585.1 transposase -
  EA667_RS03710 (EA667_003710) - 742666..744138 (+) 1473 Protein_696 phosphoethanolamine transferase -
  EA667_RS03715 (EA667_003715) ciaR 744153..744827 (+) 675 WP_000161505.1 response regulator transcription factor Regulator
  EA667_RS03720 (EA667_003720) - 744853..746187 (+) 1335 WP_000559381.1 two-component system sensor histidine kinase PmrB -
  EA667_RS03725 (EA667_003725) - 746188..746886 (-) 699 WP_000184466.1 phosphatase PAP2 family protein -
  EA667_RS03730 (EA667_003730) - 747039..748226 (-) 1188 WP_002001094.1 ammonium transporter -
  EA667_RS03740 (EA667_003740) - 748529..749413 (-) 885 WP_000144743.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25548.47 Da        Isoelectric Point: 5.3246

>NTDB_id=318631 EA667_RS03715 WP_000161505.1 744153..744827(+) (ciaR) [Acinetobacter baumannii strain TG29392]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=318631 EA667_RS03715 WP_000161505.1 744153..744827(+) (ciaR) [Acinetobacter baumannii strain TG29392]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAATTGGCGAAGACTAAATTTGATCTTATTCTTTTGGATTTAG
GATTGCCTATGATGGATGGTATGCAAGTTTTGAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAACCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAATTTGATGA
GTTGCTTGCCCGTATTCATGCATTACTACGCCGTAGTGGAGTAGAAGCTCAACTTGCGAGTCAAGATCAACTATTAGAAA
GTGGCGATCTGGTTTTAAATGTTGAACAGCATATTGCGACGTTTAAAGGTCAACGCATTGATCTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATTCGAACCA
TCCGAGGACTGGGCTACCGTTTGGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 9OF3
  PDB 9OF4
  PDB 9OF5
  PDB 9OF6
  PDB 9OF7
  PDB 9OF8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

35.965

100

0.366