Detailed information NTG0315478

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: D5R92_RS01875
• Genome accession: NZ_CP032401
• Coordinates: 392043..392768 (-)
• Length: 241 a.a.
• NCBI ID: WP_003101290.1
• Uniprot ID: A0A3L8GIX6
• Organism: Streptococcus iniae strain GX005
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 387043..397768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5R92_RS01850 (D5R92_01850)	-	387549..388160 (-)	612	WP_016356076.1	phosphate ABC transporter ATP-binding protein	-
D5R92_RS01855 (D5R92_01855)	pstA	388163..388978 (-)	816	WP_064537875.1	phosphate ABC transporter permease PstA	-
D5R92_RS01860 (D5R92_01860)	pstC	388971..389834 (-)	864	WP_003101285.1	phosphate ABC transporter permease subunit PstC	-
D5R92_RS01865 (D5R92_01865)	-	389897..390577 (-)	681	WP_016356077.1	substrate-binding domain-containing protein	-
D5R92_RS01870 (D5R92_01870)	pnpS	390731..392059 (-)	1329	WP_003101288.1	two-component system histidine kinase PnpS	-
D5R92_RS01875 (D5R92_01875)	vicR	392043..392768 (-)	726	WP_003101290.1	response regulator transcription factor	Regulator
D5R92_RS01880 (D5R92_01880)	-	392864..393247 (-)	384	WP_003101292.1	VOC family protein	-
D5R92_RS01885 (D5R92_01885)	-	393440..393583 (+)	144	WP_003101294.1	SPJ_0845 family protein	-
D5R92_RS01890 (D5R92_01890)	-	393583..394488 (+)	906	WP_003101296.1	permease	-
D5R92_RS01895 (D5R92_01895)	-	394485..395300 (+)	816	WP_016356078.1	TIGR03943 family putative permease subunit	-
D5R92_RS01900 (D5R92_01900)	-	395372..395998 (-)	627	WP_003101299.1	NAD(P)-dependent oxidoreductase	-
D5R92_RS01905 (D5R92_01905)	-	396285..397661 (-)	1377	WP_003101303.1	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 28088.34 Da
• Isoelectric Point: 5.1365

>NTDB_id=315478 D5R92_RS01875 WP_003101290.1 392043..392768(-) (vicR) [Streptococcus iniae strain GX005]
MKKTVLLVDDEEHILRLLDYHLSKEGFSIDTATDGRSALKLAETESYDFILLDIMLPQLDGIEVCKRIRAKNSKTPIMMV
SAKGEEFDKVLALELGADDYMTKPFSPRELLARVKAILRRTGKDDSQQEEFGFADQRFLVNDLVIYPERNEVYKEQDLIS
LTPKEYELLMYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDDPKNPEMIKTIRGYGYQFKEMKDATK
S

Nucleotide

• Length: 726 bp

>NTDB_id=315478 D5R92_RS01875 WP_003101290.1 392043..392768(-) (vicR) [Streptococcus iniae strain GX005]
ATGAAAAAGACAGTTTTATTAGTAGACGACGAAGAGCACATCTTACGTTTATTAGACTATCATCTCAGCAAGGAAGGCTT
TAGTATTGACACAGCAACAGATGGCAGATCAGCACTAAAATTAGCTGAAACAGAAAGTTATGACTTCATTTTGTTAGACA
TCATGTTGCCCCAATTGGACGGTATTGAGGTCTGTAAACGTATCAGAGCTAAAAATAGTAAGACCCCTATTATGATGGTA
TCAGCTAAAGGGGAAGAATTTGACAAGGTCCTAGCCTTAGAACTAGGAGCTGATGATTACATGACAAAACCCTTTAGTCC
AAGGGAATTGCTGGCGCGTGTAAAAGCTATTTTAAGACGAACAGGAAAAGACGACAGCCAACAAGAAGAGTTTGGCTTCG
CTGACCAGCGATTCTTGGTCAATGACTTGGTCATTTACCCTGAAAGAAATGAAGTTTACAAAGAGCAAGACTTGATTTCC
TTAACCCCAAAAGAGTATGAACTGTTAATGTATTTAGTCAAACATCCCAATATGACCTTAACAAGAGAACGACTTTTAGA
ACGGATTTGGGGGTATGACTTTGGCCAAGAAACACGTTTAGTAGATGTTCATATTGGAAAATTAAGAGACAAAATTGAAG
ATGATCCTAAAAATCCAGAGATGATTAAAACAATCAGGGGCTATGGCTATCAGTTTAAGGAGATGAAGGATGCTACAAAA
TCTTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-115)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (159-232)

3D structure

• AlphaFold DB: A0A3L8GIX6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	51.293	96.266	0.494
micA	Streptococcus pneumoniae Cp1015	48.918	95.851	0.469
covR	Lactococcus lactis subsp. lactis strain DGCC12653	42.194	98.34	0.415
covR	Streptococcus salivarius strain HSISS4	39.316	97.095	0.382