Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SEZ_RS04545 Genome accession   NC_011134
Coordinates   962506..963816 (+) Length   436 a.a.
NCBI ID   WP_012515549.1    Uniprot ID   A0AAW3GN95
Organism   Streptococcus equi subsp. zooepidemicus MGCS10565     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 957506..968816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEZ_RS04530 (Sez_0916) phoU 957988..958641 (+) 654 WP_012515545.1 phosphate signaling complex protein PhoU -
  SEZ_RS04535 (Sez_0917) - 958875..961412 (+) 2538 WP_012515546.1 M1 family metallopeptidase -
  SEZ_RS04540 (Sez_0919) ciaR 961839..962513 (+) 675 WP_012515548.1 response regulator transcription factor Regulator
  SEZ_RS04545 (Sez_0920) ciaH 962506..963816 (+) 1311 WP_012515549.1 HAMP domain-containing sensor histidine kinase Regulator
  SEZ_RS04550 (Sez_0921) - 964202..964633 (+) 432 WP_012515550.1 hypothetical protein -
  SEZ_RS09865 (Sez_0922) - 964715..964891 (+) 177 WP_012515551.1 hypothetical protein -
  SEZ_RS04555 (Sez_0923) - 965064..965447 (+) 384 WP_012515552.1 hypothetical protein -
  SEZ_RS04560 (Sez_0924) - 965444..965704 (+) 261 WP_012515553.1 hypothetical protein -
  SEZ_RS04565 (Sez_0925) - 965723..966133 (+) 411 WP_111721677.1 hypothetical protein -
  SEZ_RS04575 (Sez_0926) - 966348..966743 (+) 396 WP_012515555.1 hypothetical protein -
  SEZ_RS04580 (Sez_0927) - 966743..967936 (+) 1194 WP_012515556.1 hypothetical protein -
  SEZ_RS04585 (Sez_0928) - 967933..968325 (+) 393 WP_012515557.1 hypothetical protein -
  SEZ_RS04590 (Sez_0929) - 968344..968628 (+) 285 WP_012515558.1 hypothetical protein -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49574.22 Da        Isoelectric Point: 9.6507

>NTDB_id=31372 SEZ_RS04545 WP_012515549.1 962506..963816(+) (ciaH) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=31372 SEZ_RS04545 WP_012515549.1 962506..963816(+) (ciaH) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCTAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGTCAGCTCAATAACATTG
TCACCACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTTCACATCAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTCCAGCAGCTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGATAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCTAGACGCGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGACACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGACGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAAGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGCGCCATCTTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.376

100

0.514
  ciaH Streptococcus pneumoniae D39

51.376

100

0.514
  ciaH Streptococcus pneumoniae R6

51.376

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.376

100

0.514

Multiple sequence alignment