Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   D2E16_RS04925 Genome accession   NZ_CP032064
Coordinates   1033986..1035365 (+) Length   459 a.a.
NCBI ID   WP_192370208.1    Uniprot ID   -
Organism   Streptococcus suis strain YSJ17     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1028986..1040365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS04895 (D2E16_05015) pstB 1029396..1030199 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  D2E16_RS04900 (D2E16_05020) pstB 1030211..1030969 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  D2E16_RS04905 (D2E16_05025) phoU 1030998..1031654 (+) 657 WP_002940865.1 phosphate signaling complex protein PhoU -
  D2E16_RS04910 (D2E16_05030) tnpA 1031834..1032366 (+) 533 Protein_925 IS200/IS605 family transposase -
  D2E16_RS12525 - 1032629..1033177 (+) 549 WP_225620836.1 hypothetical protein -
  D2E16_RS04920 (D2E16_05045) ciaR 1033322..1033993 (+) 672 WP_002940863.1 response regulator transcription factor Regulator
  D2E16_RS04925 (D2E16_05050) ciaH 1033986..1035365 (+) 1380 WP_192370208.1 sensor histidine kinase Regulator
  D2E16_RS04930 (D2E16_05055) - 1035466..1036716 (+) 1251 WP_192370206.1 transglutaminase domain-containing protein -
  D2E16_RS04935 (D2E16_05060) - 1036861..1038349 (-) 1489 Protein_930 IS1182 family transposase -
  D2E16_RS04940 (D2E16_05065) rpsT 1038475..1038723 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  D2E16_RS04945 (D2E16_05070) coaA 1038782..1039702 (-) 921 WP_002940857.1 type I pantothenate kinase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51901.54 Da        Isoelectric Point: 6.1955

>NTDB_id=313528 D2E16_RS04925 WP_192370208.1 1033986..1035365(+) (ciaH) [Streptococcus suis strain YSJ17]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPVMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEAKVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=313528 D2E16_RS04925 WP_192370208.1 1033986..1035365(+) (ciaH) [Streptococcus suis strain YSJ17]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGTGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATCCTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAAAGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATTGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCTGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGACGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCT
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAACAAATTATCAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae D39

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae R6

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae TIGR4

49.782

99.782

0.497
  ciaH Streptococcus mutans UA159

50.336

97.386

0.49

Multiple sequence alignment