Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1101_RS04785 Genome accession   NZ_CP031866
Coordinates   1031254..1032456 (-) Length   400 a.a.
NCBI ID   WP_218633985.1    Uniprot ID   -
Organism   Actinobacillus pleuropneumoniae serovar 8 str. 405     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1026254..1037456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1101_RS04760 (D1101_04790) lptE 1028054..1028548 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  D1101_RS04765 (D1101_04795) holA 1028657..1029682 (+) 1026 WP_012263005.1 DNA polymerase III subunit delta -
  D1101_RS04770 (D1101_04800) yacG 1029759..1029947 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  D1101_RS04775 (D1101_04805) coaE 1029929..1030567 (-) 639 WP_005601202.1 dephospho-CoA kinase -
  D1101_RS04780 (D1101_04810) - 1030589..1031227 (-) 639 WP_005604550.1 prepilin peptidase -
  D1101_RS04785 (D1101_04815) pilC 1031254..1032456 (-) 1203 WP_218633985.1 type II secretion system F family protein Machinery gene
  D1101_RS04790 (D1101_04820) pilB 1032440..1033834 (-) 1395 WP_005601209.1 GspE/PulE family protein Machinery gene
  D1101_RS04795 (D1101_04825) pilA 1033852..1034298 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1101_RS04800 (D1101_04830) radA 1034480..1035859 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1101_RS04805 (D1101_04835) - 1035903..1036136 (-) 234 WP_005597399.1 YgjV family protein -
  D1101_RS04810 (D1101_04840) - 1036263..1036751 (-) 489 WP_218633986.1 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45644.15 Da        Isoelectric Point: 10.2885

>NTDB_id=312179 D1101_RS04785 WP_218633985.1 1031254..1032456(-) (pilC) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
MLKVYEFHWKAKNRFQQLQKGKALACYRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRHQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSHFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=312179 D1101_RS04785 WP_218633985.1 1031254..1032456(-) (pilC) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTTA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCCATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTTACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCACTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

50.126

99.25

0.498
  pilC Haemophilus influenzae Rd KW20

40

100

0.4
  pilC Haemophilus influenzae 86-028NP

39

100

0.39

Multiple sequence alignment