Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1105_RS04460 Genome accession   NZ_CP031862
Coordinates   995167..996369 (-) Length   400 a.a.
NCBI ID   WP_005612209.1    Uniprot ID   A0A3G2M2S7
Organism   Actinobacillus pleuropneumoniae strain 8329     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 990167..1001369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1105_RS04435 (D1105_04440) lptE 991967..992461 (+) 495 WP_005615184.1 LPS assembly lipoprotein LptE -
  D1105_RS04440 (D1105_04445) holA 992570..993595 (+) 1026 WP_043995308.1 DNA polymerase III subunit delta -
  D1105_RS04445 (D1105_04450) yacG 993672..993860 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  D1105_RS04450 (D1105_04455) coaE 993842..994480 (-) 639 WP_005601202.1 dephospho-CoA kinase -
  D1105_RS04455 (D1105_04460) - 994502..995140 (-) 639 WP_005604550.1 prepilin peptidase -
  D1105_RS04460 (D1105_04465) pilC 995167..996369 (-) 1203 WP_005612209.1 type II secretion system F family protein Machinery gene
  D1105_RS04465 (D1105_04470) pilB 996353..997747 (-) 1395 WP_005615186.1 GspE/PulE family protein Machinery gene
  D1105_RS04470 (D1105_04475) pilA 997765..998211 (-) 447 WP_005615188.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1105_RS04475 (D1105_04480) radA 998393..999772 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1105_RS04480 (D1105_04485) - 999816..1000049 (-) 234 WP_005615190.1 YgjV family protein -
  D1105_RS04485 (D1105_04490) folA 1000176..1000664 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45620.17 Da        Isoelectric Point: 10.2885

>NTDB_id=312074 D1105_RS04460 WP_005612209.1 995167..996369(-) (pilC) [Actinobacillus pleuropneumoniae strain 8329]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRYQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSLFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=312074 D1105_RS04460 WP_005612209.1 995167..996369(-) (pilC) [Actinobacillus pleuropneumoniae strain 8329]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGCTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCTATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCTCTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTTAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G2M2S7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

49.874

99.25

0.495
  pilC Haemophilus influenzae Rd KW20

40

100

0.4
  pilC Haemophilus influenzae 86-028NP

39

100

0.39

Multiple sequence alignment