Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1107_RS04305 Genome accession   NZ_CP031860
Coordinates   966210..967412 (-) Length   400 a.a.
NCBI ID   WP_237593095.1    Uniprot ID   A0A3G2M2T1
Organism   Actinobacillus pleuropneumoniae strain 3906     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 961210..972412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1107_RS04280 (D1107_04320) lptE 963010..963504 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  D1107_RS04285 (D1107_04325) holA 963613..964638 (+) 1026 WP_005601200.1 DNA polymerase III subunit delta -
  D1107_RS04290 (D1107_04330) yacG 964715..964903 (-) 189 WP_237593094.1 DNA gyrase inhibitor YacG -
  D1107_RS04295 (D1107_04335) coaE 964885..965523 (-) 639 WP_005601202.1 dephospho-CoA kinase -
  D1107_RS04300 (D1107_04340) - 965545..966183 (-) 639 WP_005604550.1 prepilin peptidase -
  D1107_RS04305 (D1107_04345) pilC 966210..967412 (-) 1203 WP_237593095.1 type II secretion system F family protein Machinery gene
  D1107_RS04310 (D1107_04350) pilB 967396..968790 (-) 1395 WP_005601209.1 GspE/PulE family protein Machinery gene
  D1107_RS04315 (D1107_04355) pilA 968808..969254 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1107_RS04320 (D1107_04360) radA 969436..970815 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1107_RS04325 (D1107_04365) - 970859..971092 (-) 234 WP_005615190.1 YgjV family protein -
  D1107_RS04330 (D1107_04370) folA 971219..971707 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45749.33 Da        Isoelectric Point: 10.2885

>NTDB_id=312022 D1107_RS04305 WP_237593095.1 966210..967412(-) (pilC) [Actinobacillus pleuropneumoniae strain 3906]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSWRLGEILQNIAVNRYQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSLFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=312022 D1107_RS04305 WP_237593095.1 966210..967412(-) (pilC) [Actinobacillus pleuropneumoniae strain 3906]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCTGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCTATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCTCTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTTAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G2M2T1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

49.622

99.25

0.492
  pilC Haemophilus influenzae Rd KW20

39.75

100

0.398
  pilC Haemophilus influenzae 86-028NP

38.75

100

0.388

Multiple sequence alignment