Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DDV21_RS06345 Genome accession   NZ_CP031733
Coordinates   1297426..1298757 (-) Length   443 a.a.
NCBI ID   WP_116877098.1    Uniprot ID   A0A372KP00
Organism   Streptococcus chenjunshii strain Z15     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1292426..1303757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS06315 (DDV21_006315) - 1292979..1293371 (-) 393 WP_116877104.1 cytidine deaminase -
  DDV21_RS06320 (DDV21_006320) deoC 1293358..1294020 (-) 663 WP_116877103.1 deoxyribose-phosphate aldolase -
  DDV21_RS06325 (DDV21_006325) - 1294032..1295309 (-) 1278 WP_116877102.1 pyrimidine-nucleoside phosphorylase -
  DDV21_RS06330 (DDV21_006330) - 1295306..1295887 (-) 582 WP_116877101.1 class I SAM-dependent methyltransferase -
  DDV21_RS06335 (DDV21_006335) coaA 1296001..1296921 (+) 921 WP_116877100.1 type I pantothenate kinase -
  DDV21_RS06340 (DDV21_006340) rpsT 1297036..1297287 (+) 252 WP_116877099.1 30S ribosomal protein S20 -
  DDV21_RS06345 (DDV21_006345) ciaH 1297426..1298757 (-) 1332 WP_116877098.1 HAMP domain-containing sensor histidine kinase Regulator
  DDV21_RS06350 (DDV21_006350) ciaR 1298747..1299421 (-) 675 WP_116877097.1 response regulator transcription factor Regulator
  DDV21_RS06355 (DDV21_006355) - 1299977..1302520 (-) 2544 WP_116877096.1 M1 family metallopeptidase -
  DDV21_RS06360 (DDV21_006360) phoU 1302563..1303216 (-) 654 WP_116877095.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 443 a.a.        Molecular weight: 49404.49 Da        Isoelectric Point: 6.0234

>NTDB_id=310836 DDV21_RS06345 WP_116877098.1 1297426..1298757(-) (ciaH) [Streptococcus chenjunshii strain Z15]
MLSKLKKKAESGDFTFFIHFFSVFTGIFLVMTVIILQVMRVGVYSSVDSNLQGAVANAEAYVSMTMSRTLLDELEDAFAG
DSSSGGGSDESDFKLKPGTEVAANTSYIVYNSKGIILNNVNTFSGLQSLKLDSSKLGQVKEVAIENYSGHAEKYHTITVA
VSSEDYPEVAYITIAINTTQLGDANSRYIKIIVVVMVIFWIISVLASVYLAKWSRKPILENYEKQKTFVENASHELRTPL
AVLQNRLETLFRKPESTILENSENIASSLDEVRNMRILTTNLLNLARRDDGLTPEIKELSPEFFDDLFDSYSLIAEENHK
VFTGINKVTRTVKTDETLLKQLLTILFDNAVKYTGQDGKIILTIRQSPDRHLLIQIADNGLGISDEDKKKIFDRFYRVDK
ARTRQSGGFGLGLSLAKQIVDSLKGTITVKDNPPQGTIFEVKL

Nucleotide


Download         Length: 1332 bp        

>NTDB_id=310836 DDV21_RS06345 WP_116877098.1 1297426..1298757(-) (ciaH) [Streptococcus chenjunshii strain Z15]
ATGCTGAGTAAATTAAAAAAGAAGGCGGAATCAGGGGATTTCACTTTCTTTATTCATTTTTTTTCTGTTTTCACCGGTAT
TTTTCTTGTGATGACAGTTATTATTTTACAAGTCATGCGGGTGGGAGTCTACTCTTCTGTAGACAGCAATCTGCAGGGGG
CAGTAGCTAATGCAGAAGCTTATGTCTCTATGACTATGTCACGCACTCTTTTAGATGAACTGGAAGATGCCTTTGCAGGG
GATTCGTCTTCGGGAGGTGGCAGCGATGAGAGCGATTTTAAGCTGAAGCCGGGAACGGAAGTGGCTGCAAATACAAGCTA
TATTGTTTATAACAGTAAGGGGATCATTTTAAATAATGTCAATACTTTTTCAGGACTGCAGTCTTTAAAACTCGACAGCA
GTAAGCTGGGGCAGGTAAAAGAAGTAGCCATTGAAAACTACTCCGGACATGCTGAAAAGTACCACACCATTACAGTTGCA
GTATCCAGCGAGGATTATCCTGAGGTTGCTTATATCACAATAGCCATTAATACAACCCAGTTAGGCGATGCCAATTCGCG
CTATATCAAAATCATTGTCGTTGTTATGGTAATTTTTTGGATTATCTCAGTTTTAGCCAGTGTATATTTGGCCAAATGGA
GCCGCAAACCTATTTTAGAAAACTATGAAAAACAAAAAACGTTTGTTGAAAACGCCAGCCATGAATTACGCACGCCGCTT
GCTGTCTTACAGAACCGCTTAGAGACCTTGTTTAGAAAACCTGAATCAACAATTCTTGAGAACAGCGAAAACATTGCTTC
AAGCCTCGATGAAGTACGAAATATGCGGATTTTGACAACTAATCTCCTGAATTTAGCCCGCAGAGATGATGGGCTGACGC
CTGAAATAAAGGAGCTATCACCTGAATTTTTTGATGATCTTTTTGACAGTTACAGTTTGATTGCTGAAGAAAACCATAAA
GTGTTTACTGGGATTAATAAAGTCACCAGAACAGTTAAAACAGATGAAACTCTTTTAAAACAGCTCCTTACCATCTTGTT
TGATAATGCTGTTAAATATACAGGACAGGATGGCAAAATTATTTTGACCATAAGACAAAGTCCAGACCGTCACCTACTGA
TTCAGATTGCTGACAATGGTCTGGGAATCAGTGATGAGGATAAAAAGAAGATCTTTGACCGCTTTTACCGTGTCGATAAA
GCCAGAACAAGGCAGAGCGGCGGCTTTGGTCTAGGCTTGTCTCTGGCCAAACAAATTGTGGATTCTCTGAAAGGCACTAT
CACAGTTAAAGACAATCCTCCGCAAGGGACCATCTTTGAAGTGAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(226-291)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(334-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KP00

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

61.851

100

0.619
  ciaH Streptococcus pneumoniae Rx1

54.484

100

0.549
  ciaH Streptococcus pneumoniae D39

54.484

100

0.549
  ciaH Streptococcus pneumoniae R6

54.484

100

0.549
  ciaH Streptococcus pneumoniae TIGR4

54.484

100

0.549

Multiple sequence alignment