Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   DDV21_RS03820 Genome accession   NZ_CP031733
Coordinates   753542..755773 (+) Length   743 a.a.
NCBI ID   WP_116878672.1    Uniprot ID   A0A372KM95
Organism   Streptococcus chenjunshii strain Z15     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 756043..756993 753542..755773 flank 270


Gene organization within MGE regions


Location: 753542..756993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS03820 (DDV21_003820) comEC/celB 753542..755773 (+) 2232 WP_116878672.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DDV21_RS03825 (DDV21_003825) - 756043..756993 (-) 951 WP_117287770.1 IS30 family transposase -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 85527.21 Da        Isoelectric Point: 9.7686

>NTDB_id=310828 DDV21_RS03820 WP_116878672.1 753542..755773(+) (comEC/celB) [Streptococcus chenjunshii strain Z15]
MINGYPIKLIHLAFLLLLLYFWFFSATILGLFLFAFALICLFRQYSWQKALLAMLILAAFAVYFGFWQKRQEKAYQEAPA
AIRYIELVSDSIAVNGDLLSFQGKSDGRKYQVFYRFQSKEEKDFFNSLSDTVILQVEGEIAEAETVRNFDGFDYRSYLKN
QGIYRLIELKNIQQFRQLSSKTPLHYLQEWRRKAVIFIQHHFPAPMRYYMTGLLFGYLDKSFDEMADLYTSLGIIHLFAL
SGMHVGFFVRLFRFCFLRLGMRRDYVDYLQIPFSFLYAALTGFSVSVMRSLVQNGFSNLGIKGVDNFALTLMTFFLIMPH
FLLIRSGILSFAYAFILILIDFSSLGRYQRKLAESLTLAIGILPLVLYFFSVFQPLSVFFTIFFSLTFEFLFLPLLTVIF
LLSPFIKITFVNSLFVLLESIINQLSQFFSRPLVLGQPQLPILILLFILLGLLYDFYHRKKLALLLTLPIALLFFSSKLP
LENEITMIDVGQGDSIFLRDMQGKTILIDVGGRPVFTNKESWQKRWGKSNAEKTLIPYLRSRGVSKIDQLVLTHADTDHV
GDLQVLAKYFKIGEILISPGSLTQNDFVQTLKAMKTEVRTVKAGDSLSIMQSRLYVLHPYQTGDGSNNDSIVLYGYLLNQ
SFLFTGDLEKEGEEKLMQLYSRLPVDVLKVGHHGSKGSTSSEFLSFIKPRYALISAGVGNRYQHPHQETLNRLKAVSVKI
YRTDLQGGIRFRGWNSWQTETVK

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=310828 DDV21_RS03820 WP_116878672.1 753542..755773(+) (comEC/celB) [Streptococcus chenjunshii strain Z15]
TTGATTAACGGTTATCCGATTAAACTGATTCATCTGGCTTTTTTACTGCTTCTGCTCTATTTTTGGTTTTTTTCTGCAAC
TATTTTAGGTCTGTTTTTATTCGCTTTTGCTCTAATCTGTCTTTTCAGGCAATACAGCTGGCAGAAAGCTTTGTTAGCAA
TGCTGATTTTAGCAGCTTTTGCTGTTTACTTTGGCTTTTGGCAGAAACGACAGGAAAAAGCTTATCAGGAAGCACCCGCT
GCGATTCGTTATATTGAGCTCGTTTCGGACAGTATTGCAGTCAACGGTGACTTGCTTTCTTTTCAAGGGAAATCTGATGG
CAGAAAATATCAAGTATTTTATCGATTCCAATCAAAAGAGGAAAAAGATTTCTTTAATAGCCTCAGTGATACTGTCATTC
TGCAGGTAGAAGGTGAGATAGCAGAAGCGGAAACAGTCCGTAATTTTGATGGTTTTGACTATCGCAGCTACTTGAAAAAT
CAGGGAATTTACCGCCTGATTGAGCTGAAAAATATCCAACAGTTCAGGCAGCTGTCATCGAAAACTCCCTTACATTATCT
GCAGGAATGGCGCCGAAAAGCTGTTATTTTTATTCAGCATCATTTTCCTGCCCCTATGAGATACTATATGACAGGCCTCT
TATTTGGCTACTTGGATAAATCTTTCGATGAAATGGCAGATCTGTATACCAGCCTTGGTATTATTCATTTATTTGCCTTA
TCAGGAATGCATGTCGGTTTCTTTGTCAGGCTTTTCCGCTTTTGCTTTTTGCGTTTAGGTATGAGGCGCGATTATGTGGA
CTATCTGCAAATTCCTTTTTCCTTTTTATATGCTGCTTTGACAGGTTTTTCTGTATCTGTTATGCGCAGTCTGGTTCAAA
ATGGTTTCTCTAATCTTGGTATTAAAGGAGTAGACAATTTTGCCCTGACCCTTATGACGTTTTTCTTGATAATGCCGCAT
TTTCTTTTGATAAGGAGTGGGATTTTATCCTTTGCCTATGCTTTTATATTGATTTTGATAGATTTTTCCAGTCTCGGCCG
CTATCAGAGAAAACTGGCTGAGTCTTTGACCCTTGCTATTGGTATTTTACCGCTAGTGCTTTATTTCTTTTCCGTTTTTC
AGCCCTTATCTGTTTTTTTTACTATTTTCTTTTCGCTGACTTTTGAATTTCTTTTTTTACCTTTGCTGACTGTCATTTTT
CTGCTTTCTCCCTTTATTAAAATAACTTTTGTCAATTCTTTATTTGTCCTTCTGGAAAGTATTATCAATCAGCTCAGTCA
GTTTTTTTCCCGTCCCTTAGTTTTAGGCCAGCCTCAGTTACCGATTCTTATTTTGCTGTTTATTTTACTGGGACTGCTTT
ATGATTTTTATCATCGAAAGAAACTGGCTTTGCTGCTGACTTTGCCGATTGCTCTTTTATTTTTCAGCAGCAAACTGCCC
TTAGAAAATGAGATAACGATGATAGATGTCGGACAGGGAGACAGTATCTTTTTAAGAGATATGCAGGGGAAAACCATTTT
GATTGACGTAGGTGGGAGACCGGTTTTCACCAATAAAGAAAGTTGGCAGAAAAGATGGGGGAAGAGCAATGCTGAGAAGA
CTCTGATCCCCTATCTGCGCAGCCGCGGGGTCAGTAAAATTGATCAGCTGGTCTTAACACATGCAGATACAGACCATGTA
GGCGATTTGCAGGTTTTGGCTAAATATTTTAAAATCGGAGAAATTTTAATCAGTCCAGGCAGTTTGACTCAGAATGATTT
TGTTCAGACCTTAAAAGCAATGAAGACTGAAGTTCGTACTGTTAAAGCAGGAGACAGTCTGTCAATTATGCAGAGCCGTT
TGTATGTTTTACACCCTTATCAAACAGGAGATGGCAGCAATAATGATTCAATAGTATTATACGGCTATCTGCTTAATCAG
AGTTTTCTATTTACAGGTGATTTAGAGAAGGAGGGGGAAGAGAAGCTGATGCAGCTTTACAGCCGTCTGCCTGTTGATGT
GTTGAAGGTAGGTCATCATGGCAGCAAGGGTTCAACAAGTTCAGAATTTTTGAGTTTTATCAAGCCTAGGTATGCTTTAA
TCTCTGCAGGTGTTGGCAACCGCTATCAGCATCCACATCAGGAAACACTGAATCGGTTAAAAGCAGTTTCTGTAAAGATT
TACCGGACAGATCTTCAAGGAGGTATACGCTTTCGGGGCTGGAACAGCTGGCAGACGGAGACTGTAAAATAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(213-456)

Metallo-beta-lactamase superfamily (Lactamase_B)

(489-697)

Domain of unknown function (DUF4131) (DUF4131)

(23-174)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KM95

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

51.609

100

0.518
  comEC/celB Streptococcus mitis SK321

51.279

100

0.513
  comEC/celB Streptococcus pneumoniae TIGR4

49.664

100

0.497
  comEC/celB Streptococcus pneumoniae Rx1

49.26

100

0.493
  comEC/celB Streptococcus pneumoniae D39

49.26

100

0.493
  comEC/celB Streptococcus pneumoniae R6

49.26

100

0.493
  comEC Lactococcus lactis subsp. cremoris KW2

47.233

99.731

0.471

Multiple sequence alignment