Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   D0T92_RS02560 Genome accession   NZ_CP031700
Coordinates   563721..565889 (+) Length   722 a.a.
NCBI ID   WP_151049939.1    Uniprot ID   A0A5J6PWQ8
Organism   Neisseria zalophi strain ATCC BAA-2455     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 542074..563153 563721..565889 flank 568


Gene organization within MGE regions


Location: 542074..565889
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D0T92_RS02470 (D0T92_02505) - 542083..542901 (+) 819 WP_191963657.1 factor H binding protein domain-containing protein -
  D0T92_RS02475 (D0T92_02510) - 543016..543993 (-) 978 WP_151049906.1 L,D-transpeptidase -
  D0T92_RS02480 (D0T92_02515) - 544923..546395 (+) 1473 WP_225315129.1 23S rRNA methyltransferase -
  D0T92_RS02485 (D0T92_02520) - 546428..547522 (+) 1095 WP_151049910.1 response regulator -
  D0T92_RS02490 (D0T92_02525) - 547546..548082 (+) 537 WP_151049912.1 ATP/GTP-binding protein -
  D0T92_RS02495 (D0T92_02530) - 548084..548725 (+) 642 WP_151049914.1 peptidase M23 -
  D0T92_RS02500 (D0T92_02535) - 548804..549166 (+) 363 WP_151049916.1 roadblock/LC7 domain-containing protein -
  D0T92_RS02505 (D0T92_02540) - 549304..551475 (-) 2172 WP_151049919.1 right-handed parallel beta-helix repeat-containing protein -
  D0T92_RS02510 (D0T92_02545) - 551799..552839 (-) 1041 WP_151049921.1 ABC transporter ATP-binding protein -
  D0T92_RS02515 (D0T92_02550) - 552836..554452 (-) 1617 WP_151049922.1 iron ABC transporter permease -
  D0T92_RS02520 (D0T92_02555) - 554695..555687 (+) 993 WP_151049924.1 Fe(3+) ABC transporter substrate-binding protein -
  D0T92_RS02525 (D0T92_02560) - 556051..556935 (+) 885 WP_151049926.1 lysophospholipid acyltransferase family protein -
  D0T92_RS02530 (D0T92_02565) rfaQ 556950..558029 (+) 1080 WP_151049928.1 putative lipopolysaccharide heptosyltransferase III -
  D0T92_RS02535 (D0T92_02570) - 558226..560646 (-) 2421 WP_151049930.1 penicillin-binding protein 1A -
  D0T92_RS02540 (D0T92_02575) pilM 560797..561894 (+) 1098 WP_404821665.1 type IV pilus assembly protein PilM -
  D0T92_RS02545 (D0T92_02580) - 561897..562514 (+) 618 WP_151049933.1 PilN domain-containing protein -
  D0T92_RS02550 (D0T92_02585) - 562518..563153 (+) 636 WP_151049935.1 type 4a pilus biogenesis protein PilO -
  D0T92_RS02555 (D0T92_02590) pilP 563173..563706 (+) 534 WP_151049937.1 pilus assembly protein PilP Machinery gene
  D0T92_RS02560 (D0T92_02595) pilQ 563721..565889 (+) 2169 WP_151049939.1 type IV pilus secretin PilQ Machinery gene

Sequence

Protein


Download         Length: 722 a.a.        Molecular weight: 79122.93 Da        Isoelectric Point: 9.6392

>NTDB_id=310541 D0T92_RS02560 WP_151049939.1 563721..565889(+) (pilQ) [Neisseria zalophi strain ATCC BAA-2455]
MNSRMTKILSAITMGFAIHSAYAGNITDINVSSLPDNQKIIKIKFDKEVVTPRGFITTTPARIALDFTGTSIQLPQPVLE
YADPLLSQITAAQNENRARILLGLNKAGQYNTEIKGNEVWVYVNEASNTTDAPPSRNNVRVSTSPAVHASAPVQKEQVVT
SANIDFRKGVRDSGIVELSAPSFTGEPEIKKQNDRITITLKNHPLPTQAQRSLDVSDFNTPVRNVTMKRIGNNTQIVIKN
KGSWDSKVQAANGRFNIEIIPKTNIASKGLDKKPKQNFNGRKISLDFQDIEVRTILQILAKESGMNIVASDTVNGRMTLS
LKDVPWDQALDLVMQARNLDMRRQGNIINVAPRDELLAKDKAALQAEKEIEDLGPLLSQTFQLKYKNVEEFRNILRLDEN
GGSTADRNSLLSNRGSALIDPATNTLIVTDNHTVMRKFQKLIEELDVPTRQVMVEARIVEANDGFSRDIGVKFGYTGVRN
NNSWGSNWNNAVNNFGTHVNNQRTIANSILSGSNTIPNTTPLEMNPNISLPVTSATASIALVRAISSGALGLELTAMQEQ
SKGKIISNPRVLTQDRKEATIESGSEIPYEEATSSGATSITFKKAVLGLTVTPNITPDGQVIMNVKINKDTPVDCVTGGV
ATKCISTKQLQTQAMVEDGGTLIVGGIYEEENGNTVSKVPLLGDIPVLGNLFKSRTRQENRRELLIFITPRIMDNLGSNL
RY

Nucleotide


Download         Length: 2169 bp        

>NTDB_id=310541 D0T92_RS02560 WP_151049939.1 563721..565889(+) (pilQ) [Neisseria zalophi strain ATCC BAA-2455]
ATGAACTCACGTATGACAAAAATTCTTTCAGCCATTACTATGGGCTTTGCCATCCATTCGGCTTATGCAGGTAATATTAC
AGATATTAATGTATCCTCATTACCTGATAATCAGAAAATCATCAAAATCAAATTTGATAAAGAGGTTGTTACACCTCGCG
GGTTTATCACAACAACACCTGCTCGTATTGCACTGGATTTCACTGGAACAAGTATTCAGTTGCCACAGCCTGTGCTGGAA
TATGCAGATCCATTGTTGAGTCAGATTACCGCGGCACAAAATGAAAATCGGGCACGCATTTTACTGGGGTTGAATAAAGC
AGGCCAATATAATACTGAAATTAAAGGTAATGAAGTTTGGGTGTATGTAAACGAAGCCTCAAATACAACCGATGCACCTC
CTTCTCGAAATAATGTTCGCGTATCAACTTCACCGGCAGTCCATGCTTCTGCGCCTGTACAAAAAGAGCAAGTTGTTACA
TCTGCCAATATCGATTTCAGAAAAGGTGTACGTGACTCCGGTATTGTAGAATTGAGCGCACCTTCTTTTACAGGTGAGCC
TGAAATTAAGAAGCAAAATGACCGTATTACCATTACTTTGAAAAATCATCCTCTGCCAACTCAAGCCCAGCGTAGTTTGG
ATGTGTCTGATTTCAATACGCCGGTACGTAATGTCACTATGAAACGTATTGGCAATAACACTCAGATTGTGATTAAAAAT
AAAGGCAGTTGGGATTCTAAAGTGCAAGCGGCTAACGGTCGTTTCAATATTGAAATTATACCTAAAACCAATATTGCTTC
AAAAGGCTTGGATAAAAAGCCTAAGCAGAATTTTAATGGGCGTAAGATTTCTTTAGACTTCCAAGATATTGAAGTACGTA
CCATATTGCAAATTTTGGCTAAAGAATCTGGTATGAATATTGTTGCCAGCGATACGGTTAATGGCAGAATGACCCTTTCC
TTGAAAGATGTGCCTTGGGATCAGGCGCTGGATTTAGTGATGCAGGCGCGTAATCTTGATATGCGTCGTCAAGGCAATAT
TATTAATGTAGCACCACGCGATGAATTGTTGGCTAAGGATAAAGCAGCATTGCAGGCAGAGAAAGAAATTGAAGATCTTG
GCCCGCTGCTTTCACAAACATTTCAATTGAAATATAAAAATGTAGAGGAATTCCGCAATATTTTGCGCTTGGATGAAAAT
GGTGGTAGCACTGCAGATAGAAACAGTTTATTGAGCAACCGCGGCAGCGCATTAATTGATCCGGCTACCAATACATTAAT
TGTTACTGATAACCATACAGTAATGCGGAAATTCCAAAAATTAATTGAAGAGCTGGATGTGCCTACCCGCCAGGTGATGG
TAGAGGCGCGTATCGTAGAAGCCAATGATGGTTTTTCTCGTGATATCGGTGTGAAATTTGGTTATACAGGTGTACGGAAT
AATAATAGCTGGGGTTCTAATTGGAACAATGCTGTGAATAATTTTGGTACTCATGTTAATAATCAACGTACGATTGCCAA
TTCTATTCTAAGCGGATCGAATACCATTCCGAATACAACACCTTTGGAAATGAATCCGAATATCAGCTTGCCGGTTACCT
CTGCAACTGCAAGCATCGCATTGGTTCGTGCCATTTCTTCAGGAGCGCTGGGGTTGGAATTGACAGCAATGCAGGAGCAA
AGCAAAGGCAAAATTATTTCTAATCCACGTGTTTTGACACAAGACCGTAAAGAAGCCACTATTGAATCTGGTTCTGAGAT
TCCTTATGAAGAAGCGACCTCTAGCGGTGCGACTTCGATTACTTTCAAAAAGGCTGTGCTTGGTTTGACGGTTACACCTA
ATATCACGCCTGATGGACAAGTAATCATGAATGTGAAAATCAATAAAGACACTCCGGTGGACTGTGTGACTGGTGGTGTT
GCTACAAAATGTATCAGCACGAAACAGTTACAAACACAAGCTATGGTTGAAGATGGTGGCACATTGATTGTCGGCGGTAT
TTATGAAGAAGAAAACGGCAACACAGTGAGCAAAGTACCTTTACTTGGCGATATCCCTGTGTTGGGTAATTTATTTAAAT
CACGTACACGTCAAGAAAACCGACGTGAGTTGTTGATCTTCATTACCCCGCGCATTATGGATAATCTTGGCAGCAACTTG
CGTTATTAA

Domains

Predicted by InterproScan.

Secretin and TonB N terminus short domain (STN)

(306-350)

Bacterial type II/III secretion system short domain (Secretin_N)

(379-451)

Bacterial type II and III secretion system protein (Secretin)

(556-714)

AMIN domain (AMIN)

(35-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5J6PWQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

57.269

100

0.627
  pilQ Neisseria meningitidis M1080

57.727

100

0.626
  pilQ Neisseria gonorrhoeae strain FA1090

60.268

100

0.622

Multiple sequence alignment