Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilP   Type   Machinery gene
Locus tag   D0T92_RS02555 Genome accession   NZ_CP031700
Coordinates   563173..563706 (+) Length   177 a.a.
NCBI ID   WP_151049937.1    Uniprot ID   A0A5J6PXA5
Organism   Neisseria zalophi strain ATCC BAA-2455     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 542074..563153 563173..563706 flank 20


Gene organization within MGE regions


Location: 542074..563706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D0T92_RS02470 (D0T92_02505) - 542083..542901 (+) 819 WP_191963657.1 factor H binding protein domain-containing protein -
  D0T92_RS02475 (D0T92_02510) - 543016..543993 (-) 978 WP_151049906.1 L,D-transpeptidase -
  D0T92_RS02480 (D0T92_02515) - 544923..546395 (+) 1473 WP_225315129.1 23S rRNA methyltransferase -
  D0T92_RS02485 (D0T92_02520) - 546428..547522 (+) 1095 WP_151049910.1 response regulator -
  D0T92_RS02490 (D0T92_02525) - 547546..548082 (+) 537 WP_151049912.1 ATP/GTP-binding protein -
  D0T92_RS02495 (D0T92_02530) - 548084..548725 (+) 642 WP_151049914.1 peptidase M23 -
  D0T92_RS02500 (D0T92_02535) - 548804..549166 (+) 363 WP_151049916.1 roadblock/LC7 domain-containing protein -
  D0T92_RS02505 (D0T92_02540) - 549304..551475 (-) 2172 WP_151049919.1 right-handed parallel beta-helix repeat-containing protein -
  D0T92_RS02510 (D0T92_02545) - 551799..552839 (-) 1041 WP_151049921.1 ABC transporter ATP-binding protein -
  D0T92_RS02515 (D0T92_02550) - 552836..554452 (-) 1617 WP_151049922.1 iron ABC transporter permease -
  D0T92_RS02520 (D0T92_02555) - 554695..555687 (+) 993 WP_151049924.1 Fe(3+) ABC transporter substrate-binding protein -
  D0T92_RS02525 (D0T92_02560) - 556051..556935 (+) 885 WP_151049926.1 lysophospholipid acyltransferase family protein -
  D0T92_RS02530 (D0T92_02565) rfaQ 556950..558029 (+) 1080 WP_151049928.1 putative lipopolysaccharide heptosyltransferase III -
  D0T92_RS02535 (D0T92_02570) - 558226..560646 (-) 2421 WP_151049930.1 penicillin-binding protein 1A -
  D0T92_RS02540 (D0T92_02575) pilM 560797..561894 (+) 1098 WP_404821665.1 type IV pilus assembly protein PilM -
  D0T92_RS02545 (D0T92_02580) - 561897..562514 (+) 618 WP_151049933.1 PilN domain-containing protein -
  D0T92_RS02550 (D0T92_02585) - 562518..563153 (+) 636 WP_151049935.1 type 4a pilus biogenesis protein PilO -
  D0T92_RS02555 (D0T92_02590) pilP 563173..563706 (+) 534 WP_151049937.1 pilus assembly protein PilP Machinery gene

Sequence


Protein


Download         Length: 177 a.a.        Molecular weight: 19493.88 Da        Isoelectric Point: 5.7814

>NTDB_id=310540 D0T92_RS02555 WP_151049937.1 563173..563706(+) (pilP) [Neisseria zalophi strain ATCC BAA-2455]
MTNKMLLAGILVLSACTPAHEDLSEWMDTTRKQAKAKVIPFEAPAVGQPKSYNPPQFSGLNAFESKRLNSVQQGTNAPDT
SRPKEILEGFSLENLKYVGSLTKGNQTKGYVEADGHVYTVSPGNYIGQNYGKIQSITADQIMITELIEDSYGNWAYRKAE
LPLMSTETNNDTAQNNK

Nucleotide


Download         Length: 534 bp        

>NTDB_id=310540 D0T92_RS02555 WP_151049937.1 563173..563706(+) (pilP) [Neisseria zalophi strain ATCC BAA-2455]
ATGACAAATAAAATGTTACTTGCAGGCATCTTGGTTTTATCAGCTTGCACACCGGCTCACGAAGATCTTAGTGAATGGAT
GGACACTACTCGTAAACAGGCAAAAGCGAAAGTCATTCCATTTGAAGCACCTGCTGTGGGTCAGCCGAAATCTTATAACC
CTCCTCAATTTAGTGGGTTAAATGCTTTTGAAAGTAAGCGGTTGAATAGCGTACAGCAAGGTACTAATGCACCTGATACA
AGTAGGCCCAAAGAAATATTGGAAGGTTTTAGTTTAGAAAATTTAAAATATGTCGGCAGTTTGACCAAAGGGAACCAGAC
AAAAGGCTATGTAGAAGCTGACGGCCATGTTTATACCGTAAGCCCGGGAAATTATATCGGACAGAACTACGGTAAAATTC
AATCTATTACTGCAGATCAAATTATGATAACGGAACTTATTGAAGACAGCTATGGAAATTGGGCTTATCGCAAAGCAGAG
TTACCTTTGATGAGTACGGAAACTAATAATGATACTGCTCAGAACAACAAATAA

Domains


Predicted by InterproScan.

(22-163)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A5J6PXA5

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilP Neisseria meningitidis MC58

54.386

96.61

0.525


Multiple sequence alignment