Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ES276_RS10010 Genome accession   NZ_CP038252
Coordinates   1975401..1975805 (-) Length   134 a.a.
NCBI ID   WP_224781841.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1970401..1980805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS09980 (ES276_10600) - 1970710..1971585 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  ES276_RS09985 (ES276_10605) pstC 1971703..1972566 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  ES276_RS09990 (ES276_10610) pstA 1972559..1973374 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  ES276_RS09995 (ES276_10615) pstB 1973376..1974128 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  ES276_RS10000 (ES276_10620) phoU 1974143..1974793 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  ES276_RS10005 (ES276_10625) - 1974810..1975286 (+) 477 Protein_1958 transposase -
  ES276_RS10010 (ES276_10630) comR 1975401..1975805 (-) 405 WP_224781841.1 helix-turn-helix transcriptional regulator Regulator
  ES276_RS10015 (ES276_10635) - 1976053..1977069 (+) 1017 WP_000415103.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ES276_RS10020 (ES276_10640) galU 1977091..1977990 (+) 900 WP_000202234.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  ES276_RS10025 (ES276_10645) - 1978408..1979349 (+) 942 WP_000428163.1 hypothetical protein -
  ES276_RS10030 (ES276_10650) - 1979451..1979636 (-) 186 WP_000693096.1 hypothetical protein -
  ES276_RS10035 (ES276_10655) - 1979650..1980327 (-) 678 WP_000658497.1 rhomboid family intramembrane serine protease -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 16159.57 Da        Isoelectric Point: 4.5898

>NTDB_id=310279 ES276_RS10010 WP_224781841.1 1975401..1975805(-) (comR) [Streptococcus pneumoniae strain TVO_1901936]
MAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETI
AQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 405 bp        

>NTDB_id=310279 ES276_RS10010 WP_224781841.1 1975401..1975805(-) (comR) [Streptococcus pneumoniae strain TVO_1901936]
TTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAA
TGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGGGGTTGAAGATTACAAGTTGATGCCAA
GTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATC
GCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCAT
CCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCT
GGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(60-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.63

80.597

0.44
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

55.66

79.104

0.44
  comR Streptococcus pyogenes MGAS315

52.778

80.597

0.425
  comR Streptococcus mutans UA159

50.926

80.597

0.41
  comR Streptococcus suis P1/7

48.113

79.104

0.381
  comR Streptococcus suis 05ZYH33

48.113

79.104

0.381
  comR Streptococcus suis D9

47.17

79.104

0.373
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

48.039

76.119

0.366

Multiple sequence alignment