Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3306_RS10250 Genome accession   NZ_CP038183
Coordinates   2069819..2070535 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain MJ015     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2064819..2075535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3306_RS10220 (E3306_10695) - 2065038..2065664 (+) 627 WP_000522384.1 nitroreductase family protein -
  E3306_RS10225 (E3306_10700) - 2066025..2066810 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  E3306_RS14170 (E3306_10705) - 2067407..2067541 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  E3306_RS10235 (E3306_10710) agrB 2067777..2068346 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  E3306_RS10240 (E3306_10715) agrD 2068343..2068483 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  E3306_RS10245 (E3306_10720) agrC 2068508..2069800 (+) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  E3306_RS10250 (E3306_10725) agrA 2069819..2070535 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  E3306_RS10255 (E3306_10730) - 2070607..2070716 (+) 110 Protein_1995 hypothetical protein -
  E3306_RS10260 (E3306_10735) - 2070904..2071863 (-) 960 WP_001253310.1 carbohydrate kinase -
  E3306_RS10265 (E3306_10740) - 2071860..2073344 (-) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  E3306_RS10270 (E3306_10745) - 2073493..2074443 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=309822 E3306_RS10250 WP_000688498.1 2069819..2070535(+) (agrA) [Staphylococcus aureus strain MJ015]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=309822 E3306_RS10250 WP_000688498.1 2069819..2070535(+) (agrA) [Staphylococcus aureus strain MJ015]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment