Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   E3C75_RS03010 Genome accession   NZ_CP038020
Coordinates   561749..563110 (-) Length   453 a.a.
NCBI ID   WP_111679175.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 556749..568110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS02990 - 559013..559354 (+) 342 WP_024404826.1 LytTR family DNA-binding domain-containing protein -
  E3C75_RS02995 comE/blpR 559356..560096 (+) 741 WP_111679174.1 response regulator transcription factor Regulator
  E3C75_RS03000 - 560107..561447 (+) 1341 WP_039671036.1 GHKL domain-containing protein -
  E3C75_RS03005 - 561495..561650 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  E3C75_RS03010 comB 561749..563110 (-) 1362 WP_111679175.1 bacteriocin secretion accessory protein Regulator
  E3C75_RS03015 - 563122..565276 (-) 2155 Protein_553 peptide cleavage/export ABC transporter -
  E3C75_RS03020 - 565574..565831 (+) 258 WP_039671027.1 Blp family class II bacteriocin -
  E3C75_RS03025 - 565848..566027 (+) 180 WP_111679177.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  E3C75_RS03030 - 566629..567979 (+) 1351 Protein_556 IS3 family transposase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 50325.41 Da        Isoelectric Point: 5.2958

>NTDB_id=309209 E3C75_RS03010 WP_111679175.1 561749..563110(-) (comB) [Streptococcus thermophilus strain ATCC 19258]
MNPNLFKSAEFYQRRYHNFATHLIVPLILLVGFLLTFSLFAQKEVTVTSRGEITPTTIIASIQSTSNNPITTNNLANNKL
VKKNELIIQYAETMESSQKQALETQLATLNRQKTGLETLKESLSQGTNLFTGEDEFGYINTFNNFITQSQDIELGISKTN
AEVSNQAALAGNTIAAIDTQINQIYHQIAEYEELRQAITNRQTSLSADNPHQATLNNFLAQSQQDSQTGLTDQYLSQINQ
SISGLESSIASLNIQRAGTGSVATYDNSFVTKVEVLRTQFLQSASQQLTTLETQITELVAQLEQASVRLENNTITAPETG
VIHLNSEFEGKSLIPSGSEIAQIYPNINQTKEFLITYYVTSEHVALLKEKQDVRLSLEKVGNQSITVVGKIKSIDKTATK
TEEGNLFKVTALAQLSDKHSDVIQYGLQGRVTSIIAKKTYFDYYKDKILSNHD

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=309209 E3C75_RS03010 WP_111679175.1 561749..563110(-) (comB) [Streptococcus thermophilus strain ATCC 19258]
ATGAACCCTAATTTGTTCAAAAGTGCTGAATTTTACCAGCGGCGCTACCATAATTTTGCGACACACTTAATTGTCCCCTT
GATATTATTAGTCGGCTTTCTTCTAACCTTCTCCCTTTTTGCCCAAAAGGAGGTTACCGTCACATCAAGAGGTGAAATTA
CTCCGACGACAATCATCGCTTCCATCCAATCCACCAGCAATAACCCTATCACAACCAATAATCTAGCCAATAACAAGCTG
GTTAAAAAGAATGAGCTCATCATCCAATACGCTGAAACTATGGAGAGTTCCCAAAAACAAGCCCTTGAAACCCAGCTAGC
CACTCTAAATAGACAGAAAACTGGACTTGAAACCCTCAAAGAAAGCCTGTCACAGGGAACGAACCTCTTTACAGGGGAGG
ACGAATTTGGCTATATCAATACTTTTAACAACTTTATCACCCAGTCACAGGACATCGAACTAGGAATTTCCAAAACCAAT
GCAGAGGTGAGTAACCAGGCCGCCCTAGCAGGTAATACCATTGCTGCGATTGACACGCAAATCAATCAAATCTATCACCA
AATAGCAGAATACGAGGAGCTTCGTCAAGCCATTACCAATAGACAGACCAGTTTATCAGCTGACAATCCACACCAAGCCA
CCTTAAACAATTTCTTAGCCCAATCCCAACAAGACTCCCAGACAGGATTAACTGATCAATACCTTTCTCAAATCAACCAA
AGTATCTCAGGGCTAGAATCATCCATAGCTAGTCTGAACATCCAACGAGCTGGAACTGGCTCTGTTGCAACCTATGATAA
CAGCTTTGTAACAAAGGTTGAGGTCCTAAGAACACAGTTTTTACAATCGGCCTCTCAGCAGCTGACCACCCTTGAAACGC
AAATCACAGAGCTAGTGGCACAGCTAGAGCAAGCATCCGTCCGACTAGAAAACAATACCATTACAGCTCCTGAAACAGGG
GTAATCCATCTCAATAGTGAGTTTGAAGGAAAGTCTTTGATTCCAAGCGGTAGTGAAATCGCTCAGATTTACCCCAATAT
CAATCAAACCAAAGAATTCCTCATTACTTACTACGTGACTTCAGAACATGTCGCCTTACTCAAAGAAAAACAAGACGTGC
GCCTGAGCTTAGAAAAAGTTGGCAACCAAAGCATCACTGTTGTTGGAAAAATTAAGTCTATCGATAAAACTGCTACTAAA
ACTGAGGAGGGGAATCTTTTCAAAGTTACTGCCTTGGCTCAACTATCCGACAAGCATAGCGACGTCATCCAGTACGGTCT
CCAGGGTCGAGTCACAAGTATCATTGCCAAGAAGACTTACTTTGATTACTACAAGGATAAAATTTTATCCAACCATGATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

38.444

99.338

0.382
  comB Streptococcus pneumoniae D39

38.444

99.338

0.382
  comB Streptococcus pneumoniae R6

38.444

99.338

0.382
  comB Streptococcus pneumoniae TIGR4

38.222

99.338

0.38
  comB Streptococcus mitis SK321

37.639

99.117

0.373
  comB Streptococcus mitis NCTC 12261

37.639

99.117

0.373