Detailed information NTG0308807

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZQ17_RS07355
• Genome accession: NZ_CP031632
• Coordinates: 1457549..1458550 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28078
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1452549..1463550

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZQ17_RS07340 (DZQ17_07335)	thrS	1452719..1454662 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZQ17_RS07345 (DZQ17_07340)	-	1455084..1456418 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZQ17_RS07350 (DZQ17_07345)	-	1456420..1457418 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZQ17_RS07355 (DZQ17_07350)	ccpA	1457549..1458550 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZQ17_RS07360 (DZQ17_07355)	-	1458724..1459809 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZQ17_RS07365 (DZQ17_07360)	-	1459858..1460523 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZQ17_RS07370 (DZQ17_07365)	-	1460534..1460911 (+)	378	WP_002985686.1	VOC family protein	-
DZQ17_RS07375 (DZQ17_07370)	-	1461056..1461982 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZQ17_RS07380 (DZQ17_07375)	-	1462193..1462876 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308807 DZQ17_RS07355 WP_002985680.1 1457549..1458550(-) (ccpA) [Streptococcus pyogenes strain MGAS28078]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308807 DZQ17_RS07355 WP_002985680.1 1457549..1458550(-) (ccpA) [Streptococcus pyogenes strain MGAS28078]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559