Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   EZ612_RS05455 Genome accession   NZ_CP036531
Coordinates   1090231..1091193 (-) Length   320 a.a.
NCBI ID   WP_031488550.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain STAB10048     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1085231..1096193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZ612_RS05440 (EZ612_05515) - 1086067..1086774 (-) 708 WP_002984000.1 O-methyltransferase -
  EZ612_RS05445 (EZ612_05520) - 1086840..1088036 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  EZ612_RS05450 (EZ612_05525) pepF 1088413..1090218 (-) 1806 WP_011054652.1 oligoendopeptidase F Regulator
  EZ612_RS05455 (EZ612_05530) coiA 1090231..1091193 (-) 963 WP_031488550.1 competence protein CoiA Machinery gene
  EZ612_RS05460 (EZ612_05535) - 1091489..1092205 (-) 717 WP_002995774.1 pseudouridine synthase -
  EZ612_RS05465 (EZ612_05540) nagB 1092324..1093028 (-) 705 WP_002995779.1 glucosamine-6-phosphate deaminase -
  EZ612_RS05470 (EZ612_05545) queA 1093230..1094258 (+) 1029 WP_031488549.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  EZ612_RS05475 (EZ612_05550) - 1094265..1095485 (+) 1221 WP_002983986.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37847.33 Da        Isoelectric Point: 10.2438

>NTDB_id=308274 EZ612_RS05455 WP_031488550.1 1090231..1091193(-) (coiA) [Streptococcus pyogenes strain STAB10048]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
CLSFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=308274 EZ612_RS05455 WP_031488550.1 1090231..1091193(-) (coiA) [Streptococcus pyogenes strain STAB10048]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
TGTTTGAGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.581

96.875

0.413
  coiA Streptococcus pneumoniae Rx1

41.29

96.875

0.4
  coiA Streptococcus pneumoniae D39

41.29

96.875

0.4
  coiA Streptococcus pneumoniae R6

41.29

96.875

0.4
  coiA Streptococcus pneumoniae TIGR4

41.29

96.875

0.4
  coiA Lactococcus lactis subsp. cremoris KW2

39.024

100

0.4

Multiple sequence alignment