Detailed information NTG0308274

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZV70_RS07435
• Genome accession: NZ_CP031622
• Coordinates: 1457348..1458349 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28686
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1452348..1463349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZV70_RS07420 (DZV70_07415)	thrS	1452518..1454461 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZV70_RS07425 (DZV70_07420)	-	1454883..1456217 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZV70_RS07430 (DZV70_07425)	-	1456219..1457217 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZV70_RS07435 (DZV70_07430)	ccpA	1457348..1458349 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZV70_RS07440 (DZV70_07435)	-	1458523..1459608 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZV70_RS07445 (DZV70_07440)	-	1459657..1460322 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZV70_RS07450 (DZV70_07445)	-	1460333..1460710 (+)	378	WP_002985686.1	VOC family protein	-
DZV70_RS07455 (DZV70_07450)	-	1460855..1461781 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZV70_RS07460 (DZV70_07455)	-	1461992..1462675 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308274 DZV70_RS07435 WP_002985680.1 1457348..1458349(-) (ccpA) [Streptococcus pyogenes strain MGAS28686]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308274 DZV70_RS07435 WP_002985680.1 1457348..1458349(-) (ccpA) [Streptococcus pyogenes strain MGAS28686]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559