Detailed information NTG0030627

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: SPCG_RS09290
• Genome accession: NC_010582
• Coordinates: 1777985..1778644 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565023.1
• Uniprot ID: A0A0I8D2P0
• Organism: Streptococcus pneumoniae CGSP14
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1772985..1783644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPCG_RS09265 (SPCG_1788)	-	1773290..1773607 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
SPCG_RS09270 (SPCG_1789)	-	1773622..1774518 (-)	897	WP_000825669.1	PEP phosphonomutase	-
SPCG_RS09275 (SPCG_1790)	-	1774521..1775783 (-)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
SPCG_RS09280 (SPCG_1791)	-	1776063..1777241 (+)	1179	WP_000175881.1	ROK family transcriptional regulator	-
SPCG_RS09285 (SPCG_1792)	-	1777469..1777915 (-)	447	WP_000155407.1	GNAT family N-acetyltransferase	-
SPCG_RS09290 (SPCG_1794)	cclA/cilC	1777985..1778644 (+)	660	WP_000565023.1	A24 family peptidase	Machinery gene
SPCG_RS09295 (SPCG_1795)	trpA	1778616..1779392 (-)	777	WP_001127001.1	tryptophan synthase subunit alpha	-
SPCG_RS09300 (SPCG_1796)	trpB	1779385..1780608 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
SPCG_RS09305 (SPCG_1797)	-	1780586..1781185 (-)	600	WP_000169909.1	phosphoribosylanthranilate isomerase	-
SPCG_RS09310 (SPCG_1798)	trpC	1781172..1781939 (-)	768	WP_000076548.1	indole-3-glycerol phosphate synthase TrpC	-
SPCG_RS09315 (SPCG_1799)	trpD	1781936..1782940 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
SPCG_RS09320 (SPCG_1800)	-	1782951..1783517 (-)	567	WP_000601921.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24921.13 Da
• Isoelectric Point: 8.2409

>NTDB_id=30627 SPCG_RS09290 WP_000565023.1 1777985..1778644(+) (cclA/cilC) [Streptococcus pneumoniae CGSP14]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=30627 SPCG_RS09290 WP_000565023.1 1777985..1778644(+) (cclA/cilC) [Streptococcus pneumoniae CGSP14]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

3D structure

• AlphaFold DB: A0A0I8D2P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	97.717	100	0.977
cclA/cilC	Streptococcus pneumoniae Rx1	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae D39	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae R6	96.347	100	0.963
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863