Detailed information NTG0305836

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: DV163_RS07010
• Genome accession: NZ_CP031330
• Coordinates: 1184486..1185346 (+)
• Length: 286 a.a.
• NCBI ID: WP_003710975.1
• Uniprot ID: A0A1V0DRE8
• Organism: Neisseria meningitidis strain M21955
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1179486..1190346

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV163_RS06990	dapD	1180149..1180970 (-)	822	WP_002216408.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
DV163_RS06995	-	1180980..1181210 (-)	231	WP_009348191.1	hypothetical protein	-
DV163_RS07000	pgi	1181180..1182823 (-)	1644	WP_002224874.1	glucose-6-phosphate isomerase	-
DV163_RS07005	pilG	1183180..1184412 (+)	1233	WP_115437302.1	type 4 pilus assembly protein PilG	Machinery gene
DV163_RS07010	pilD	1184486..1185346 (+)	861	WP_003710975.1	A24 family peptidase	Machinery gene
DV163_RS07015	coaE	1185348..1185980 (+)	633	WP_002224873.1	dephospho-CoA kinase	-
DV163_RS07020	-	1185973..1186182 (+)	210	WP_002224872.1	DNA gyrase inhibitor YacG	-
DV163_RS07025	pilF	1186267..1187943 (-)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
DV163_RS07040	-	1188355..1188831 (-)	477	WP_079254847.1	DUF441 domain-containing protein	-
DV163_RS07045	ispB	1188836..1189810 (-)	975	WP_002216396.1	octaprenyl diphosphate synthase	-
DV163_RS07055	rplU	1190034..1190342 (+)	309	WP_002216394.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31231.27 Da
• Isoelectric Point: 8.7141

>NTDB_id=305836 DV163_RS07010 WP_003710975.1 1184486..1185346(+) (pilD) [Neisseria meningitidis strain M21955]
MFALSVLPPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPSIELLTGVLFGLVAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=305836 DV163_RS07010 WP_003710975.1 1184486..1185346(+) (pilD) [Neisseria meningitidis strain M21955]
ATGTTTGCTTTATCTGTACTGCCTCCGTTTGCCGTACCTTTGGCAGCGGTGTTGGGACTGCTGGTCGGCAGTTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTGATGATGGAGCGCGGTTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGATGAGGAAAGCCGCACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCGAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTACCC
CTCTATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCATTATGGCTCTTATGTGCGGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCAGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: A0A1V0DRE8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	97.193	99.65	0.969
pilD	Acinetobacter baumannii D1279779	48.485	92.308	0.448
pilD	Acinetobacter nosocomialis M2	48.485	92.308	0.448
pilD	Vibrio campbellii strain DS40M4	44.251	100	0.444
pilD	Vibrio cholerae strain A1552	46.014	96.503	0.444