Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EXA02_RS13890 Genome accession   NZ_CP035841
Coordinates   2871827..2872459 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain TW10722     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2866827..2877459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA02_RS13865 yhfG 2866959..2867126 (+) 168 WP_000736860.1 YhfG family protein -
  EXA02_RS13870 fic 2867116..2867718 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EXA02_RS13875 pabA 2867750..2868313 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  EXA02_RS13880 argD 2868399..2869619 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EXA02_RS13885 yhfK 2869686..2871776 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  EXA02_RS13890 crp 2871827..2872459 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EXA02_RS13895 yhfA 2872761..2873165 (+) 405 WP_001148908.1 OsmC family protein -
  EXA02_RS13900 prkB 2873220..2874089 (-) 870 WP_001274680.1 phosphoribulokinase -
  EXA02_RS13905 yheU 2874143..2874361 (-) 219 WP_000907085.1 YheU family protein -
  EXA02_RS13910 yheT 2874355..2875377 (-) 1023 WP_000057405.1 hydrolase -
  EXA02_RS13915 yheS 2875377..2877290 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=305656 EXA02_RS13890 WP_000242755.1 2871827..2872459(-) (crp) [Escherichia coli strain TW10722]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=305656 EXA02_RS13890 WP_000242755.1 2871827..2872459(-) (crp) [Escherichia coli strain TW10722]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTTCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment