Detailed information NTG0305122

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: DV445_RS02715
• Genome accession: NZ_CP031255
• Coordinates: 540450..541322 (+)
• Length: 290 a.a.
• NCBI ID: WP_107853522.1
• Uniprot ID: -
• Organism: Neisseria elongata strain M15910
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	537512..552081	540450..541322	within	0

Gene organization within MGE regions

Location: 537512..552081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV445_RS02705	pilF	537512..539191 (+)	1680	WP_107853523.1	type IV-A pilus assembly ATPase PilB	Machinery gene
DV445_RS02710	pilG	539216..540439 (+)	1224	WP_049248630.1	type II secretion system F family protein	Machinery gene
DV445_RS02715	pilD	540450..541322 (+)	873	WP_107853522.1	prepilin peptidase	Machinery gene
DV445_RS02720	coaE	541322..541924 (+)	603	WP_114921596.1	dephospho-CoA kinase	-
DV445_RS02725	zapD	541939..542700 (+)	762	WP_114921597.1	cell division protein ZapD	-
DV445_RS02730	-	542697..542903 (+)	207	WP_107853519.1	DNA gyrase inhibitor YacG	-
DV445_RS02735	rpmE	543035..543253 (-)	219	WP_049248635.1	50S ribosomal protein L31	-
DV445_RS02740	-	543388..543606 (-)	219	WP_107853518.1	SlyX family protein	-
DV445_RS02745	-	543607..544989 (-)	1383	WP_107853517.1	Na+/H+ antiporter family protein	-
DV445_RS02750	-	545282..546256 (-)	975	WP_234404629.1	hypothetical protein	-
DV445_RS02755	-	546424..547749 (+)	1326	WP_114921598.1	M23 family metallopeptidase	-
DV445_RS02760	-	548044..552081 (-)	4038	WP_162817619.1	pilus assembly protein	-

Sequence

Protein

• Length: 290 a.a.
• Molecular weight: 31781.79 Da
• Isoelectric Point: 8.2411

>NTDB_id=305122 DV445_RS02715 WP_107853522.1 540450..541322(+) (pilD) [Neisseria elongata strain M15910]
MHAWITETYSSWIVQLAIVFGLLVGSFLNVVIYRIPVMMEREWTVFAKTHLNIALTDDEKEPFSLTKPASRCPKCGSSVK
PWQNIPVLSYILLKGQCHKCHVHISLRYPLIEILTACVFGIVAVCYGWSWITLAGFIFSAILIALTFIDADTQYLPDELT
NPLIWLGLLANSTGNGLVDLKQSLLGAVFGYLSLWLLNKIHKTIRGIDGIGGGDFKLLAALGAWLGSFVLPIIVLVAAII
GILAAVVMKVAKSQPIAFGPSLAIAGWVVFIAYDKVIAGVNWWLHQSGFA

Nucleotide

• Length: 873 bp

>NTDB_id=305122 DV445_RS02715 WP_107853522.1 540450..541322(+) (pilD) [Neisseria elongata strain M15910]
ATGCATGCATGGATTACAGAAACTTATTCTTCTTGGATCGTTCAGTTAGCCATTGTCTTTGGTTTATTAGTTGGCAGTTT
TTTAAATGTAGTGATCTATCGTATTCCTGTTATGATGGAACGCGAGTGGACTGTTTTCGCAAAGACACACCTAAATATTG
CTTTAACTGATGACGAAAAAGAGCCATTTAGTTTAACTAAACCGGCATCACGATGTCCAAAATGTGGAAGTTCGGTAAAG
CCTTGGCAGAATATACCCGTGCTGAGTTATATTTTATTGAAGGGCCAATGTCATAAGTGCCACGTCCATATCAGTTTGCG
GTATCCATTGATTGAAATCTTGACTGCTTGTGTATTCGGCATTGTTGCAGTCTGTTATGGATGGTCTTGGATCACTTTAG
CGGGTTTTATCTTTTCCGCAATTTTGATAGCGTTGACATTCATTGATGCGGATACTCAATATTTACCTGATGAGCTTACT
AATCCTTTAATTTGGTTGGGATTGTTGGCTAATTCTACAGGGAATGGGTTGGTGGATTTGAAACAATCACTTTTAGGAGC
CGTATTTGGATATTTAAGTTTATGGTTGTTGAATAAAATACATAAAACGATTCGCGGTATAGATGGAATCGGTGGTGGGG
ATTTTAAATTGTTAGCAGCTTTAGGGGCTTGGTTGGGTAGTTTTGTATTACCTATAATAGTCCTTGTTGCGGCAATAATC
GGTATCCTGGCTGCCGTAGTTATGAAAGTTGCGAAGAGTCAGCCTATCGCATTTGGTCCCAGCTTAGCTATTGCTGGATG
GGTGGTGTTTATTGCCTATGATAAAGTGATTGCTGGGGTGAATTGGTGGTTGCACCAGTCAGGGTTTGCATAG

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (137-245)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (19-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	61.011	95.517	0.583
pilD	Vibrio campbellii strain DS40M4	44.84	96.897	0.434
pilD	Vibrio cholerae strain A1552	46.067	92.069	0.424
pilD	Acinetobacter baumannii D1279779	43.682	95.517	0.417
pilD	Acinetobacter nosocomialis M2	43.321	95.517	0.414