Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DV446_RS06870 Genome accession   NZ_CP031252
Coordinates   1349217..1350089 (-) Length   290 a.a.
NCBI ID   WP_074894938.1    Uniprot ID   A0A378U1Y3
Organism   Neisseria elongata strain M15911     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1344217..1355089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV446_RS06835 - 1344271..1345245 (+) 975 WP_240317838.1 hypothetical protein -
  DV446_RS06840 - 1345538..1346920 (+) 1383 WP_074894944.1 Na+/H+ antiporter family protein -
  DV446_RS06845 - 1346921..1347139 (+) 219 WP_003769492.1 SlyX family protein -
  DV446_RS06850 rpmE 1347274..1347492 (+) 219 WP_049248635.1 50S ribosomal protein L31 -
  DV446_RS06855 - 1347648..1347842 (-) 195 WP_049253000.1 DNA gyrase inhibitor YacG -
  DV446_RS06860 zapD 1347839..1348600 (-) 762 WP_074894942.1 cell division protein ZapD -
  DV446_RS06865 coaE 1348615..1349217 (-) 603 WP_074894940.1 dephospho-CoA kinase -
  DV446_RS06870 pilD 1349217..1350089 (-) 873 WP_074894938.1 prepilin peptidase Machinery gene
  DV446_RS06875 pilG 1350100..1351323 (-) 1224 WP_049248630.1 type II secretion system F family protein Machinery gene
  DV446_RS06880 pilF 1351348..1353027 (-) 1680 WP_074894936.1 type IV-A pilus assembly ATPase PilB Machinery gene
  DV446_RS06885 - 1353159..1354748 (-) 1590 WP_074894934.1 inorganic phosphate transporter -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 31733.84 Da        Isoelectric Point: 8.4749

>NTDB_id=305022 DV446_RS06870 WP_074894938.1 1349217..1350089(-) (pilD) [Neisseria elongata strain M15911]
MHAWINEAYAPWIVQLAVVFGLLVGSFLNVVIYRIPVMMERKWTVFAKTHLNIALTDDEKEPFSLTKPASRCPKCGSSVK
PWQNIPVLSYILLKGQCHKCHDHISLRYPLIEILTACVFGIVAVCYGWSWITLAGFIFSAILIALTFIDADTQYLPDELT
NPLIWLGLLVNSTGNGLVDLKQSLLGAIFGYLSLWLLNKIHKTIRGIDGIGGGDFKLLAALGAWLGSLVLPIIVLVAAII
GILAAVVMKVAKSQPIAFGPSLAIAGWVVFIAYDKVIAGVNWWLHQSGLA

Nucleotide


Download         Length: 873 bp        

>NTDB_id=305022 DV446_RS06870 WP_074894938.1 1349217..1350089(-) (pilD) [Neisseria elongata strain M15911]
ATGCATGCATGGATAAATGAAGCTTATGCTCCTTGGATTGTTCAGTTAGCTGTTGTCTTTGGTTTATTAGTGGGCAGTTT
TTTAAATGTAGTGATCTATCGTATTCCTGTTATGATGGAGCGCAAGTGGACTGTTTTCGCAAAGACACACCTAAATATTG
CTTTAACTGATGACGAAAAAGAGCCATTTAGTTTAACTAAACCGGCATCACGATGTCCAAAATGTGGAAGCTCGGTAAAG
CCTTGGCAGAATATACCCGTGCTAAGTTATATTTTGTTGAAGGGACAATGCCATAAGTGCCACGATCATATCAGTTTGCG
GTATCCATTGATTGAAATCTTGACTGCTTGTGTATTCGGCATTGTTGCAGTCTGTTATGGATGGTCTTGGATCACTTTAG
CGGGTTTTATCTTTTCCGCAATTTTGATAGCGTTGACATTCATTGATGCAGATACTCAATATTTACCTGATGAACTTACT
AATCCTTTAATTTGGTTGGGATTGTTGGTTAATTCTACAGGGAATGGATTGGTGGATTTGAAACAATCCCTTTTAGGAGC
CATATTTGGATATTTAAGTTTATGGTTGTTGAATAAAATACATAAAACGATTCGCGGTATAGATGGAATCGGTGGTGGGG
ATTTTAAATTGTTAGCAGCTTTAGGGGCGTGGTTGGGTAGTTTGGTATTACCTATAATAGTCCTTGTTGCAGCAATAATC
GGCATCCTGGCTGCCGTAGTTATGAAAGTTGCGAAGAGTCAGCCTATCGCATTCGGTCCCAGCTTAGCTATTGCTGGATG
GGTAGTGTTTATTGCCTATGATAAAGTGATTGCTGGGGTAAATTGGTGGTTGCACCAGTCGGGGTTGGCATAG

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(137-245)

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(19-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A378U1Y3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

60.65

95.517

0.579
  pilD Vibrio campbellii strain DS40M4

44.84

96.897

0.434
  pilD Vibrio cholerae strain A1552

45.091

94.828

0.428
  pilD Acinetobacter baumannii D1279779

46.124

88.966

0.41
  pilD Acinetobacter nosocomialis M2

45.736

88.966

0.407

Multiple sequence alignment