Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV378_RS05015 Genome accession   NZ_CP031249
Coordinates   1010721..1011941 (-) Length   406 a.a.
NCBI ID   WP_050948984.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M15895     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1005721..1016941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV378_RS04980 - 1006896..1007102 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DV378_RS04985 - 1007176..1007382 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV378_RS04990 - 1007468..1007674 (-) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  DV378_RS04995 cueR 1007751..1008137 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DV378_RS05000 metJ 1008151..1008468 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DV378_RS05005 rho 1008716..1009978 (+) 1263 WP_005629550.1 transcription termination factor Rho -
  DV378_RS05010 pilD 1010032..1010724 (-) 693 WP_050948983.1 A24 family peptidase Machinery gene
  DV378_RS05015 pilC 1010721..1011941 (-) 1221 WP_050948984.1 type II secretion system F family protein Machinery gene
  DV378_RS05020 pilB 1011938..1013332 (-) 1395 WP_005691826.1 GspE/PulE family protein Machinery gene
  DV378_RS05025 pilA 1013329..1013778 (-) 450 WP_005691824.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV378_RS05030 ampD 1013893..1014447 (+) 555 WP_005691822.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV378_RS05035 corC 1015079..1015978 (+) 900 WP_114934782.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46226.47 Da        Isoelectric Point: 9.9010

>NTDB_id=304922 DV378_RS05015 WP_050948984.1 1010721..1011941(-) (pilC) [Haemophilus influenzae strain M15895]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGITHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLERLLQSIEAGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=304922 DV378_RS05015 WP_050948984.1 1010721..1011941(-) (pilC) [Haemophilus influenzae strain M15895]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGATTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAAGCTGGTTT
AGCATTTTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGCAAACTAGCCGTAGTTTGTAAAAAAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATCATGTTGTACCCCTCAATGGTGTTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATTTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAACATATTGCGGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCAGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

98.522

100

0.985
  pilC Haemophilus influenzae 86-028NP

98.276

100

0.983
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment