Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DV130_RS10680 Genome accession   NZ_CP031248
Coordinates   1959063..1959722 (-) Length   219 a.a.
NCBI ID   WP_000565607.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26365     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1954063..1964722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS10650 - 1954243..1954842 (+) 600 WP_000169898.1 phosphoribosylanthranilate isomerase -
  DV130_RS10655 trpB 1954820..1956043 (+) 1224 WP_024477621.1 tryptophan synthase subunit beta -
  DV130_RS10660 trpA 1956036..1956812 (+) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  DV130_RS12270 - 1956784..1956885 (-) 102 Protein_1987 prepilin peptidase -
  DV130_RS10670 - 1957114..1957845 (+) 732 WP_000934017.1 hypothetical protein -
  DV130_RS10675 - 1957860..1959011 (+) 1152 WP_000481744.1 XRE family transcriptional regulator -
  DV130_RS10680 cclA/cilC 1959063..1959722 (-) 660 WP_000565607.1 A24 family peptidase Machinery gene
  DV130_RS10685 - 1959792..1960238 (+) 447 WP_050072388.1 GNAT family N-acetyltransferase -
  DV130_RS10690 - 1960466..1961644 (-) 1179 WP_050072387.1 ROK family transcriptional regulator -
  DV130_RS10695 - 1961918..1963180 (+) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  DV130_RS10700 - 1963183..1964079 (+) 897 WP_000825664.1 PEP phosphonomutase -
  DV130_RS10705 - 1964094..1964411 (+) 318 WP_114865203.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24826.93 Da        Isoelectric Point: 7.3241

>NTDB_id=304889 DV130_RS10680 WP_000565607.1 1959063..1959722(-) (cclA/cilC) [Streptococcus pneumoniae strain M26365]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLHPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=304889 DV130_RS10680 WP_000565607.1 1959063..1959722(-) (cclA/cilC) [Streptococcus pneumoniae strain M26365]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCATCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment