Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   DV130_RS08160 Genome accession   NZ_CP031248
Coordinates   1528757..1529419 (+) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain M26365     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1523757..1534419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS08120 tnpB 1524221..1524544 (+) 324 WP_000973416.1 IS66 family insertion sequence element accessory protein TnpB -
  DV130_RS08125 - 1524685..1524974 (-) 290 Protein_1557 transposase -
  DV130_RS08130 - 1524977..1525491 (+) 515 Protein_1558 transposase -
  DV130_RS08140 cysK 1525566..1526486 (-) 921 WP_050072351.1 cysteine synthase A -
  DV130_RS08150 - 1526771..1527406 (-) 636 WP_050072350.1 YigZ family protein -
  DV130_RS08155 comFA/cflA 1527462..1528760 (+) 1299 WP_000867608.1 DEAD/DEAH box helicase Machinery gene
  DV130_RS08160 comFC/cflB 1528757..1529419 (+) 663 WP_000649971.1 ComF family protein Machinery gene
  DV130_RS08165 raiA 1529499..1530047 (+) 549 WP_000599104.1 ribosome-associated translation inhibitor RaiA -
  DV130_RS08170 - 1530183..1532156 (+) 1974 WP_114865186.1 DHH family phosphoesterase -
  DV130_RS08175 rplI 1532153..1532605 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  DV130_RS08180 dnaB 1532649..1534001 (+) 1353 WP_000852486.1 replicative DNA helicase -
  DV130_RS08185 - 1534003..1534269 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=304857 DV130_RS08160 WP_000649971.1 1528757..1529419(+) (comFC/cflB) [Streptococcus pneumoniae strain M26365]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=304857 DV130_RS08160 WP_000649971.1 1528757..1529419(+) (comFC/cflB) [Streptococcus pneumoniae strain M26365]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment