Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DV129_RS10555 Genome accession   NZ_CP031247
Coordinates   1916398..1917057 (-) Length   219 a.a.
NCBI ID   WP_000565003.1    Uniprot ID   A0A0E9GWM6
Organism   Streptococcus pneumoniae strain M23734     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1911398..1922057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS10525 - 1911578..1912177 (+) 600 WP_000169909.1 phosphoribosylanthranilate isomerase -
  DV129_RS10530 trpB 1912155..1913378 (+) 1224 WP_000331296.1 tryptophan synthase subunit beta -
  DV129_RS10535 trpA 1913371..1914147 (+) 777 WP_001126994.1 tryptophan synthase subunit alpha -
  DV129_RS12010 - 1914119..1914220 (-) 102 Protein_1932 prepilin peptidase -
  DV129_RS10545 - 1914449..1915180 (+) 732 Protein_1933 hypothetical protein -
  DV129_RS10550 - 1915195..1916346 (+) 1152 WP_000481750.1 XRE family transcriptional regulator -
  DV129_RS10555 cclA/cilC 1916398..1917057 (-) 660 WP_000565003.1 A24 family peptidase Machinery gene
  DV129_RS10560 - 1917127..1917573 (+) 447 WP_000155414.1 GNAT family N-acetyltransferase -
  DV129_RS10565 - 1917801..1918979 (-) 1179 WP_000175876.1 ROK family transcriptional regulator -
  DV129_RS10570 - 1919259..1920521 (+) 1263 WP_114865993.1 PTS sugar transporter subunit IIC -
  DV129_RS10575 - 1920524..1921420 (+) 897 WP_000825669.1 PEP phosphonomutase -
  DV129_RS10580 - 1921435..1921752 (+) 318 WP_001151646.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24841.94 Da        Isoelectric Point: 7.6166

>NTDB_id=304814 DV129_RS10555 WP_000565003.1 1916398..1917057(-) (cclA/cilC) [Streptococcus pneumoniae strain M23734]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=304814 DV129_RS10555 WP_000565003.1 1916398..1917057(-) (cclA/cilC) [Streptococcus pneumoniae strain M23734]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCATAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E9GWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae Rx1

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae D39

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae R6

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment