Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   DV129_RS08270 Genome accession   NZ_CP031247
Coordinates   1519673..1520335 (+) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain M23734     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1514673..1525335
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS08235 tnpB 1515144..1515431 (+) 288 WP_000973412.1 IS66 family insertion sequence element accessory protein TnpB -
  DV129_RS08240 - 1515622..1515890 (-) 269 Protein_1552 transposase -
  DV129_RS08245 - 1515893..1516407 (+) 515 Protein_1553 transposase -
  DV129_RS08255 cysK 1516482..1517402 (-) 921 WP_000029860.1 cysteine synthase A -
  DV129_RS08260 - 1517687..1518322 (-) 636 WP_000395739.1 YigZ family protein -
  DV129_RS08265 comFA/cflA 1518378..1519676 (+) 1299 WP_000867601.1 DEAD/DEAH box helicase Machinery gene
  DV129_RS08270 comFC/cflB 1519673..1520335 (+) 663 WP_000649974.1 ComF family protein Machinery gene
  DV129_RS08275 raiA 1520415..1520963 (+) 549 WP_000599104.1 ribosome-associated translation inhibitor RaiA -
  DV129_RS08280 - 1521099..1523072 (+) 1974 WP_114865985.1 DHH family phosphoesterase -
  DV129_RS08285 rplI 1523069..1523521 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  DV129_RS08290 dnaB 1523565..1524917 (+) 1353 WP_000852486.1 replicative DNA helicase -
  DV129_RS08295 - 1524919..1525185 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=304782 DV129_RS08270 WP_000649974.1 1519673..1520335(+) (comFC/cflB) [Streptococcus pneumoniae strain M23734]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=304782 DV129_RS08270 WP_000649974.1 1519673..1520335(+) (comFC/cflB) [Streptococcus pneumoniae strain M23734]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment