Detailed information NTG0304752

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DV129_RS03120
• Genome accession: NZ_CP031247
• Coordinates: 584340..585293 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain M23734
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 579340..590293

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV129_RS03090	-	579830..579925 (-)	96	Protein_589	IS630 family transposase	-
DV129_RS03100	-	580338..580679 (+)	342	Protein_590	IS3 family transposase	-
DV129_RS03105	prsA	580796..581737 (-)	942	WP_000727933.1	peptidylprolyl isomerase PrsA	-
DV129_RS03110	-	581804..582517 (-)	714	WP_000230399.1	O-methyltransferase	-
DV129_RS03115	pepF	582519..584321 (-)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
DV129_RS03120	coiA	584340..585293 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
DV129_RS03125	tehB	585366..586226 (-)	861	WP_000413758.1	SAM-dependent methyltransferase TehB	-
DV129_RS03130	smpB	586242..586709 (-)	468	WP_001051753.1	SsrA-binding protein SmpB	-
DV129_RS03135	rnr	586672..589026 (-)	2355	WP_000654877.1	ribonuclease R	-
DV129_RS03140	secG	589128..589361 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
DV129_RS03145	rpmG	589401..589550 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=304752 DV129_RS03120 WP_000495909.1 584340..585293(-) (coiA) [Streptococcus pneumoniae strain M23734]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=304752 DV129_RS03120 WP_000495909.1 584340..585293(-) (coiA) [Streptococcus pneumoniae strain M23734]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435