Detailed information NTG0304648

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DV119_RS07830
• Genome accession: NZ_CP031245
• Coordinates: 1434944..1435897 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain M16808
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1429944..1440897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV119_RS07805	rpmG	1430687..1430836 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
DV119_RS07810	secG	1430876..1431109 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
DV119_RS07815	rnr	1431211..1433565 (+)	2355	WP_054387412.1	ribonuclease R	-
DV119_RS07820	smpB	1433528..1433995 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
DV119_RS07825	tehB	1434011..1434871 (+)	861	WP_054387413.1	SAM-dependent methyltransferase TehB	-
DV119_RS07830	coiA	1434944..1435897 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
DV119_RS07835	pepF	1435916..1437727 (+)	1812	WP_114880829.1	oligoendopeptidase F	Regulator
DV119_RS07840	-	1437729..1438442 (+)	714	WP_000230399.1	O-methyltransferase	-
DV119_RS07845	prsA	1438509..1439450 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
DV119_RS07850	-	1439567..1439947 (-)	381	Protein_1438	transposase	-
DV119_RS07860	-	1440360..1440455 (+)	96	Protein_1439	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=304648 DV119_RS07830 WP_000495909.1 1434944..1435897(+) (coiA) [Streptococcus pneumoniae strain M16808]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=304648 DV119_RS07830 WP_000495909.1 1434944..1435897(+) (coiA) [Streptococcus pneumoniae strain M16808]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435