Detailed information NTG0304407

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DV441_RS06580
• Genome accession: NZ_CP031238
• Coordinates: 1360632..1361753 (-)
• Length: 373 a.a.
• NCBI ID: WP_046953340.1
• Uniprot ID: A0A0M3G833
• Organism: Haemophilus haemolyticus strain M28486
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1355632..1366753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV441_RS06555	-	1356595..1357383 (+)	789	WP_005636887.1	outer membrane protein assembly factor BamD	-
DV441_RS06560	smpB	1357435..1357917 (-)	483	WP_005633362.1	SsrA-binding protein SmpB	-
DV441_RS06565	pfkA	1358156..1359121 (-)	966	WP_005627427.1	6-phosphofructokinase	-
DV441_RS06570	-	1359229..1359810 (-)	582	WP_046953342.1	hypothetical protein	-
DV441_RS06575	yaaA	1359803..1360579 (-)	777	WP_046953341.1	peroxide stress protein YaaA	-
DV441_RS06580	dprA	1360632..1361753 (-)	1122	WP_046953340.1	DNA-processing protein DprA	Machinery gene
DV441_RS06585	leuA	1362298..1363845 (+)	1548	WP_046953339.1	2-isopropylmalate synthase	-
DV441_RS06590	leuB	1364020..1365096 (+)	1077	WP_046953338.1	3-isopropylmalate dehydrogenase	-
DV441_RS06595	leuC	1365188..1366597 (+)	1410	WP_046953337.1	3-isopropylmalate dehydratase large subunit	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41787.00 Da
• Isoelectric Point: 5.6587

>NTDB_id=304407 DV441_RS06580 WP_046953340.1 1360632..1361753(-) (dprA) [Haemophilus haemolyticus strain M28486]
MQDITYTLLRLMQVPKLGGVGIDKILSNITLDELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALEWSQKEGNHLVNS
FSPFYPFLLKQIASFPPLLFVKGNLTALSQRQIAMVGSRYCTAYGEYWAKYFATELSLAGFTITSGLALGIDGHCHQAVV
DIQGQTIAVLGSGLEQIYPVKHRKLSELILQNNGTLISEFLPNQAPIATNFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQSEFSQGCNRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQITVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIMSENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=304407 DV441_RS06580 WP_046953340.1 1360632..1361753(-) (dprA) [Haemophilus haemolyticus strain M28486]
ATGCAAGATATTACCTACACACTACTCCGCCTAATGCAAGTCCCTAAACTTGGCGGAGTGGGAATTGATAAAATTTTATC
CAATATTACGCTAGATGAGTTGCTCAATTATGATGATGTTGCTTTCCGACAAATGGGATGGGGCGCCATTCAAATTCGTC
GTTGGTTCAAGCCTGAAGCAAAATTTATTGAGCCTGCGCTAGAGTGGTCTCAAAAAGAGGGGAATCATTTGGTAAATTCT
TTTTCCCCCTTTTATCCCTTTCTATTGAAACAGATAGCAAGCTTTCCTCCTCTGCTATTTGTAAAAGGAAATTTGACCGC
ACTTTCACAACGTCAAATTGCGATGGTGGGAAGTCGCTACTGCACGGCTTATGGTGAATATTGGGCTAAATATTTTGCTA
CGGAACTTTCATTGGCTGGCTTTACGATTACCAGTGGACTCGCATTGGGAATAGATGGGCATTGCCATCAAGCAGTTGTT
GATATTCAAGGACAAACCATTGCAGTTTTAGGAAGCGGATTAGAACAAATTTATCCCGTAAAGCATCGCAAACTTTCAGA
GCTCATTTTGCAAAACAACGGTACATTAATTTCTGAGTTTTTACCAAACCAAGCACCTATTGCGACAAATTTCCCTCGTC
GTAATAGAATTATTAGCGGGCTTTCGGTCGGGACATTAGTGGTGGAAGCCACAGAAAAAAGCGGTTCTCTGATTACCGCT
CGGTATGCATTAGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAGTGAATTTAGCCAAGGTTGTAATCG
CCTAATTAAACAAGGCGCAATGTTGGTGGAAAATGCAAAGGATATTTTGGAAACCCTATACCAACATTCTATCCATAGCC
AAACTGAAATCGATTTTGACCAGATCACAGTGCCTAATTACACGCCACCACCCGATCCTCGCCGATTGGTAGAAGCACCA
AGTCACCCGAAACTTTATTCGCGTATCGGTTACACGCCTGTGAGCATTGATGATTTAGCTGAAGAATTTAACTTGAGTGT
CGATGTTTTACTTGTTCAGTTGCTCGATCTTGAATTGCAAGATCTCATCATGAGTGAAAATGGGCTATATAAACGCGTTT
AG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

• DprA winged helix domain (DprA_WH) (311-367)

3D structure

• AlphaFold DB: A0A0M3G833

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	93.298	100	0.933
dprA	Glaesserella parasuis strain SC1401	51.149	93.298	0.477
dprA	Vibrio campbellii strain DS40M4	43.207	98.66	0.426
dprA	Vibrio cholerae strain A1552	42.742	99.732	0.426
dprA	Legionella pneumophila strain ERS1305867	42.121	88.472	0.373