Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV400_RS01390 Genome accession   NZ_CP031236
Coordinates   270984..272204 (-) Length   406 a.a.
NCBI ID   WP_050948984.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M25267     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 265984..277204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV400_RS01350 - 266867..267073 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DV400_RS01355 - 267159..267365 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV400_RS01360 - 267439..267645 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV400_RS01365 - 267731..267937 (-) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  DV400_RS01370 cueR 268014..268400 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DV400_RS01375 metJ 268414..268731 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DV400_RS01380 rho 268979..270241 (+) 1263 WP_005629550.1 transcription termination factor Rho -
  DV400_RS01385 pilD 270295..270987 (-) 693 WP_050948983.1 A24 family peptidase Machinery gene
  DV400_RS01390 pilC 270984..272204 (-) 1221 WP_050948984.1 type II secretion system F family protein Machinery gene
  DV400_RS01395 pilB 272201..273595 (-) 1395 WP_005691826.1 GspE/PulE family protein Machinery gene
  DV400_RS01400 pilA 273592..274041 (-) 450 WP_005691824.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV400_RS01405 ampD 274156..274710 (+) 555 WP_005691822.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV400_RS01410 corC 275342..276241 (+) 900 WP_050948985.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46226.47 Da        Isoelectric Point: 9.9010

>NTDB_id=304323 DV400_RS01390 WP_050948984.1 270984..272204(-) (pilC) [Haemophilus influenzae strain M25267]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGITHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLERLLQSIEAGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=304323 DV400_RS01390 WP_050948984.1 270984..272204(-) (pilC) [Haemophilus influenzae strain M25267]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGATTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAAGCTGGTTT
AGCATTTTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGCAAACTAGCCGTAGTTTGTAAAAAAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATCATGTTGTACCCCTCAATGGTGTTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATTTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAACATATTGCGGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCAGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

98.522

100

0.985
  pilC Haemophilus influenzae 86-028NP

98.276

100

0.983
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment