Detailed information NTG0302387

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DR994_RS08810
• Genome accession: NZ_CP030927
• Coordinates: 1713282..1713719 (-)
• Length: 145 a.a.
• NCBI ID: WP_022096897.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CS9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1708282..1718719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DR994_RS08775 (DR994_09000)	-	1708340..1709002 (-)	663	WP_002946116.1	type II CAAX endopeptidase family protein	-
DR994_RS08780 (DR994_09005)	-	1709105..1709548 (-)	444	WP_002946118.1	hypothetical protein	-
DR994_RS10170 (DR994_09010)	-	1709622..1709960 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
DR994_RS08790 (DR994_09015)	-	1710291..1710488 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
DR994_RS08795 (DR994_09020)	-	1710737..1711930 (-)	1194	WP_022096898.1	acetate kinase	-
DR994_RS08800 (DR994_09025)	comYH	1711986..1712942 (-)	957	WP_173940669.1	class I SAM-dependent methyltransferase	Machinery gene
DR994_RS08805 (DR994_09030)	comGG	1712987..1713304 (-)	318	WP_141326604.1	competence type IV pilus minor pilin ComGG	-
DR994_RS08810 (DR994_09035)	comYF	1713282..1713719 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
DR994_RS08815 (DR994_09040)	comGE	1713703..1713996 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
DR994_RS08820 (DR994_09045)	comYD	1713968..1714396 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
DR994_RS08825 (DR994_09050)	comYC	1714356..1714682 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
DR994_RS08830 (DR994_09055)	comYB	1714679..1715779 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
DR994_RS08835 (DR994_09060)	comGA/cglA/cilD	1715661..1716602 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
DR994_RS08840 (DR994_09065)	-	1716683..1717045 (-)	363	WP_173940670.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.89 Da
• Isoelectric Point: 8.9784

>NTDB_id=302387 DR994_RS08810 WP_022096897.1 1713282..1713719(-) (comYF) [Streptococcus thermophilus strain CS9]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=302387 DR994_RS08810 WP_022096897.1 1713282..1713719(-) (comYF) [Streptococcus thermophilus strain CS9]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	46.809	97.241	0.455
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441