Detailed information NTG0302389

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: DR994_RS08825
• Genome accession: NZ_CP030927
• Coordinates: 1714356..1714682 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain CS9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1709356..1719682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DR994_RS10170 (DR994_09010)	-	1709622..1709960 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
DR994_RS08790 (DR994_09015)	-	1710291..1710488 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
DR994_RS08795 (DR994_09020)	-	1710737..1711930 (-)	1194	WP_022096898.1	acetate kinase	-
DR994_RS08800 (DR994_09025)	comYH	1711986..1712942 (-)	957	WP_173940669.1	class I SAM-dependent methyltransferase	Machinery gene
DR994_RS08805 (DR994_09030)	comGG	1712987..1713304 (-)	318	WP_141326604.1	competence type IV pilus minor pilin ComGG	-
DR994_RS08810 (DR994_09035)	comYF	1713282..1713719 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
DR994_RS08815 (DR994_09040)	comGE	1713703..1713996 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
DR994_RS08820 (DR994_09045)	comYD	1713968..1714396 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
DR994_RS08825 (DR994_09050)	comYC	1714356..1714682 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
DR994_RS08830 (DR994_09055)	comYB	1714679..1715779 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
DR994_RS08835 (DR994_09060)	comGA/cglA/cilD	1715661..1716602 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
DR994_RS08840 (DR994_09065)	-	1716683..1717045 (-)	363	WP_173940670.1	DUF1033 family protein	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=302389 DR994_RS08825 WP_002946126.1 1714356..1714682(-) (comYC) [Streptococcus thermophilus strain CS9]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=302389 DR994_RS08825 WP_002946126.1 1714356..1714682(-) (comYC) [Streptococcus thermophilus strain CS9]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361