Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DR994_RS02120 Genome accession   NZ_CP030927
Coordinates   393044..394426 (-) Length   460 a.a.
NCBI ID   WP_173940374.1    Uniprot ID   A0A2H4K9L9
Organism   Streptococcus thermophilus strain CS9     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 388044..399426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DR994_RS02095 (DR994_02145) - 388269..388655 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  DR994_RS09800 - 388713..389520 (-) 808 Protein_369 GNAT family N-acetyltransferase -
  DR994_RS02100 (DR994_02155) yidA 389728..390537 (+) 810 WP_011226081.1 sugar-phosphatase -
  DR994_RS02105 (DR994_02160) - 390539..391753 (+) 1215 WP_173940373.1 aminoacyltransferase -
  DR994_RS02110 (DR994_02165) - 391805..392166 (-) 362 Protein_372 YbaN family protein -
  DR994_RS02115 (DR994_02170) vicX 392226..393038 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  DR994_RS02120 (DR994_02175) vicK 393044..394426 (-) 1383 WP_173940374.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DR994_RS02125 (DR994_02180) vicR 394419..395126 (-) 708 WP_173940375.1 response regulator YycF Regulator
  DR994_RS02130 (DR994_02185) - 395653..396420 (+) 768 WP_173940376.1 amino acid ABC transporter ATP-binding protein -
  DR994_RS02135 (DR994_02190) - 396432..397265 (+) 834 WP_022096756.1 transporter substrate-binding domain-containing protein -
  DR994_RS02140 (DR994_02195) - 397283..397981 (+) 699 WP_022096755.1 amino acid ABC transporter permease -
  DR994_RS02145 (DR994_02200) - 397993..398643 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 460 a.a.        Molecular weight: 52434.98 Da        Isoelectric Point: 5.1451

>NTDB_id=302343 DR994_RS02120 WP_173940374.1 393044..394426(-) (vicK) [Streptococcus thermophilus strain CS9]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLNDLSDVFRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETAIQMSILDILDGEN
PYTYSELLSKTPEIHLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSV
KSYLEALDDGALNEEIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPG
KSYEIIRDYPVNSIWVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYR
VDKARSRAQGGTGLGLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1383 bp        

>NTDB_id=302343 DR994_RS02120 WP_173940374.1 393044..394426(-) (vicK) [Streptococcus thermophilus strain CS9]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAACTTGAATGATTTGTCGGACGTCTTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAA
CCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTATTGCGACCAATCGCCTTGGTCAGATTACTATGATTAATA
GTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGATTCAGATGTCTATTTTGGATATATTAGATGGTGAGAAT
CCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATCCATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGAC
GCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTTTATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTG
AGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAAATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTG
AAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAAGAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGA
AACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATTATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTG
AAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATCGGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGT
AAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATTTGGGTGGAAATTGATACTGATAAGATGACCCAGGTCAT
AGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGGTGGGAAAATTACAGTATCTATGAAAACGACAGACACTC
AGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTAAAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGT
GTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTTGGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAA
TGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAACTTTTACAATTGTGCTTCCATATGACCAGGACGCAATGA
TGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(37-79)

His Kinase A (phospho-acceptor) domain (HisKA)

(222-286)

PAS fold (PAS)

(108-211)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(339-449)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2H4K9L9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

72.196

93.043

0.672
  micB Streptococcus pneumoniae Cp1015

64

97.826

0.626

Multiple sequence alignment