Detailed information NTG0302084

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: ETT59_RS00340
• Genome accession: NZ_CP035440
• Coordinates: 53987..54985 (+)
• Length: 332 a.a.
• NCBI ID: WP_053308139.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm124
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 48987..59985

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT59_RS00325 (ETT59_00325)	-	49988..51406 (+)	1419	WP_011888524.1	hypothetical protein	-
ETT59_RS00330 (ETT59_00330)	purB	51427..52719 (+)	1293	WP_014407197.1	adenylosuccinate lyase	-
ETT59_RS00335 (ETT59_00335)	comR	52850..53761 (+)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
ETT59_RS09300	comS	53845..53940 (+)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
ETT59_RS00340 (ETT59_00340)	ruvB	53987..54985 (+)	999	WP_053308139.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
ETT59_RS00345 (ETT59_00345)	-	55123..55560 (+)	438	WP_002994668.1	low molecular weight protein-tyrosine-phosphatase	-
ETT59_RS00350 (ETT59_00350)	-	55583..55984 (+)	402	WP_012560369.1	MORN repeat-containing protein	-
ETT59_RS00355 (ETT59_00355)	-	55981..57756 (+)	1776	WP_053308140.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37611.14 Da
• Isoelectric Point: 5.1564

>NTDB_id=302084 ETT59_RS00340 WP_053308139.1 53987..54985(+) (ruvB) [Streptococcus pyogenes strain emm124]
MARILDNNVMGNEEFSDWTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
SQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=302084 ETT59_RS00340 WP_053308139.1 53987..54985(+) (ruvB) [Streptococcus pyogenes strain emm124]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATTGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTAGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
TCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAAATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.545	99.398	0.84
ruvB	Streptococcus pneumoniae D39	84.545	99.398	0.84
ruvB	Streptococcus pneumoniae TIGR4	84.242	99.398	0.837
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473