Detailed information NTG0301744

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DRA66_RS09830
• Genome accession: NZ_CP030825
• Coordinates: 1970940..1972133 (+)
• Length: 397 a.a.
• NCBI ID: WP_002216225.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain 12-208
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1965940..1977133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DRA66_RS09815 (DRA66_11615)	-	1966863..1967462 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
DRA66_RS09820 (DRA66_11620)	-	1967462..1969579 (+)	2118	WP_002247928.1	PAS domain-containing sensor histidine kinase	-
DRA66_RS09825 (DRA66_11625)	-	1969572..1970849 (+)	1278	WP_002247929.1	sigma-54 dependent transcriptional regulator	-
DRA66_RS09830 (DRA66_11630)	dprA	1970940..1972133 (+)	1194	WP_002216225.1	DNA-processing protein DprA	Machinery gene
DRA66_RS09835 (DRA66_11635)	-	1972159..1972620 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
DRA66_RS09840 (DRA66_11640)	topA	1972692..1974998 (+)	2307	WP_002224383.1	type I DNA topoisomerase	-
DRA66_RS09845 (DRA66_11645)	-	1975071..1975766 (-)	696	WP_002216227.1	hypothetical protein	-
DRA66_RS09850 (DRA66_11655)	-	1976457..1976834 (+)	378	WP_002247931.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 42654.87 Da
• Isoelectric Point: 6.3983

>NTDB_id=301744 DRA66_RS09830 WP_002216225.1 1970940..1972133(+) (dprA) [Neisseria meningitidis strain 12-208]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVALAVRHKQAAEAWRNAEKRASARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAERGLIVSEFPLDTRPFAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPRLLQNEGASSYSINKGMPEKRITAVQT
ASDQLSLPEGKMPSEKTENRPVGGSILDRMGFDPVHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1194 bp

>NTDB_id=301744 DRA66_RS09830 WP_002216225.1 1970940..1972133(+) (dprA) [Neisseria meningitidis strain 12-208]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCTGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCCTCGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCCGTCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCGTTGCAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCTTATGAAATTGCCGAAAGGGGATTGATTGTCAGCGAGTTCCCTTTGGACACGCGTCCGTTTG
CAGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCACTGTCGCAAGTAACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGTTTGGCGGCAGAAATGGGGCGCGAGGTAATGGCGGTACCCGGTTCGATAGACAACCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGCCTGGACGACATCCTGAACGAATGCCCGC
GGCTCTTGCAAAATGAGGGTGCTTCGTCATATTCTATAAATAAGGGAATGCCTGAAAAGCGCATCACTGCCGTTCAGACG
GCATCCGACCAGCTGTCTCTGCCTGAAGGCAAAATGCCGTCTGAAAAGACGGAGAACCGACCCGTCGGCGGCAGTATCTT
GGACAGGATGGGTTTCGACCCAGTTCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCG
CACTGTTGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (344-390)

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	94.962	100	0.95
dprA	Neisseria meningitidis MC58	94.962	100	0.95
dprA	Neisseria gonorrhoeae strain FA1090	89.421	100	0.894
dprA	Neisseria gonorrhoeae MS11	89.169	100	0.892
dprA	Vibrio cholerae strain A1552	37.845	100	0.38
dprA	Vibrio campbellii strain DS40M4	36.99	98.741	0.365