Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ETT67_RS08810 Genome accession   NZ_CP035432
Coordinates   1741372..1741968 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain emm11     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1736372..1746968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT67_RS08775 (ETT67_08765) - 1736431..1736736 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ETT67_RS08780 (ETT67_08770) ruvX 1736748..1737167 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ETT67_RS08785 (ETT67_08775) - 1737164..1737433 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ETT67_RS08790 (ETT67_08780) spx 1737548..1737946 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ETT67_RS08795 (ETT67_08785) recA 1738237..1739373 (-) 1137 WP_023612576.1 recombinase RecA Machinery gene
  ETT67_RS08800 (ETT67_08790) cinA 1739462..1740733 (-) 1272 WP_038434334.1 competence/damage-inducible protein A Machinery gene
  ETT67_RS08805 (ETT67_08795) - 1740802..1741362 (-) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  ETT67_RS08810 (ETT67_08800) ruvA 1741372..1741968 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  ETT67_RS08815 (ETT67_08805) - 1741970..1743190 (-) 1221 WP_136019698.1 MFS transporter -
  ETT67_RS08820 (ETT67_08810) hexB 1743201..1745183 (-) 1983 WP_038434338.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=301417 ETT67_RS08810 WP_002992186.1 1741372..1741968(-) (ruvA) [Streptococcus pyogenes strain emm11]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=301417 ETT67_RS08810 WP_002992186.1 1741372..1741968(-) (ruvA) [Streptococcus pyogenes strain emm11]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419