Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ETT68_RS07255 Genome accession   NZ_CP035431
Coordinates   1424758..1425540 (-) Length   260 a.a.
NCBI ID   WP_136099187.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm105     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1419758..1430540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT68_RS07225 (ETT68_07220) gatB 1419838..1421277 (-) 1440 WP_010922602.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  ETT68_RS07230 (ETT68_07225) gatA 1421277..1422743 (-) 1467 WP_136099186.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  ETT68_RS07235 (ETT68_07230) gatC 1422743..1423045 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  ETT68_RS07240 (ETT68_07235) - 1423277..1423597 (-) 321 Protein_1344 putative PEP-binding protein -
  ETT68_RS07250 (ETT68_07245) - 1424057..1424611 (-) 555 WP_002992568.1 cysteine hydrolase family protein -
  ETT68_RS07255 (ETT68_07250) codY 1424758..1425540 (-) 783 WP_136099187.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ETT68_RS07260 (ETT68_07255) - 1425758..1426972 (-) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  ETT68_RS07265 (ETT68_07260) - 1427203..1427655 (+) 453 WP_168435454.1 universal stress protein -
  ETT68_RS07270 (ETT68_07265) - 1427778..1429166 (-) 1389 WP_136099189.1 Cof-type HAD-IIB family hydrolase -
  ETT68_RS07275 (ETT68_07270) - 1429238..1430203 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28632.78 Da        Isoelectric Point: 4.6228

>NTDB_id=301309 ETT68_RS07255 WP_136099187.1 1424758..1425540(-) (codY) [Streptococcus pyogenes strain emm105]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNNNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=301309 ETT68_RS07255 WP_136099187.1 1424758..1425540(-) (codY) [Streptococcus pyogenes strain emm105]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATAACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.759

98.846

0.65
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment