Detailed information NTG0301146

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: ETT69_RS00340
• Genome accession: NZ_CP035430
• Coordinates: 55029..56027 (+)
• Length: 332 a.a.
• NCBI ID: WP_002986679.1
• Uniprot ID: A2RC05
• Organism: Streptococcus pyogenes strain emm55
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 50029..61027

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT69_RS00325 (ETT69_00325)	-	50760..52457 (+)	1698	WP_136019557.1	AIPR family protein	-
ETT69_RS00330 (ETT69_00330)	purB	52475..53767 (+)	1293	WP_136019556.1	adenylosuccinate lyase	-
ETT69_RS00335 (ETT69_00335)	comR	53898..54809 (+)	912	WP_136019555.1	XRE family transcriptional regulator	Regulator
ETT69_RS09805	comS	54900..54998 (+)	99	WP_020833188.1	quorum-sensing system DWW-type pheromone	Regulator
ETT69_RS00340 (ETT69_00340)	ruvB	55029..56027 (+)	999	WP_002986679.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
ETT69_RS00345 (ETT69_00345)	-	56165..56602 (+)	438	WP_136019554.1	low molecular weight protein-tyrosine-phosphatase	-
ETT69_RS00350 (ETT69_00350)	-	56625..57026 (+)	402	WP_002986671.1	MORN repeat-containing protein	-
ETT69_RS00355 (ETT69_00355)	-	57023..58798 (+)	1776	WP_136019553.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37565.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=301146 ETT69_RS00340 WP_002986679.1 55029..56027(+) (ruvB) [Streptococcus pyogenes strain emm55]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=301146 ETT69_RS00340 WP_002986679.1 55029..56027(+) (ruvB) [Streptococcus pyogenes strain emm55]
ATGGCTAGAATTTTAGATAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGGCCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACTCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: A2RC05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473