Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DP112_RS04255 Genome accession   NZ_CP030125
Coordinates   841718..843097 (+) Length   459 a.a.
NCBI ID   WP_105135003.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 836718..848097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS04225 (DP112_04225) pstA 837096..837983 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  DP112_RS04230 (DP112_04230) pstB 838008..838811 (+) 804 WP_114866431.1 phosphate ABC transporter ATP-binding protein PstB -
  DP112_RS04235 (DP112_04235) pstB 838823..839581 (+) 759 WP_114866432.1 phosphate ABC transporter ATP-binding protein PstB -
  DP112_RS04240 (DP112_04240) phoU 839610..840266 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  DP112_RS04245 (DP112_04245) - 840432..840860 (+) 429 WP_114866433.1 hypothetical protein -
  DP112_RS04250 (DP112_04250) ciaR 841054..841725 (+) 672 WP_024385291.1 response regulator transcription factor Regulator
  DP112_RS04255 (DP112_04255) ciaH 841718..843097 (+) 1380 WP_105135003.1 HAMP domain-containing sensor histidine kinase Regulator
  DP112_RS04260 (DP112_04260) - 843198..844427 (+) 1230 WP_105134493.1 transglutaminase domain-containing protein -
  DP112_RS04265 (DP112_04265) rpsT 844692..844940 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  DP112_RS04270 (DP112_04270) coaA 844999..845919 (-) 921 WP_002935283.1 type I pantothenate kinase -
  DP112_RS04275 (DP112_04275) - 846028..846618 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  DP112_RS04280 (DP112_04280) - 846615..847892 (+) 1278 WP_002940851.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51959.63 Da        Isoelectric Point: 6.1945

>NTDB_id=299481 DP112_RS04255 WP_105135003.1 841718..843097(+) (ciaH) [Streptococcus suis strain HA1003]
MPKRIRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLLLDKEKLGEIKEATVESSFGM
SEDYRYVTIELAIDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=299481 DP112_RS04255 WP_105135003.1 841718..843097(+) (ciaH) [Streptococcus suis strain HA1003]
ATGCCTAAGCGAATCAGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATTATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCCGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACTGTTAGATAAGGAAAAATTGGGTGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTATAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAGATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTTATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAACAA
AAGGACTTTGTCGAAAATGCTAGTCATGAGTTGCGTACGCCGCTGGCTGTTCTCCAAAATCGTTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACTTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAACTATTTTGAT
GAAATATTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTCACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACACGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGTTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGACTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.676

100

0.501
  ciaH Streptococcus pneumoniae D39

49.676

100

0.501
  ciaH Streptococcus pneumoniae R6

49.676

100

0.501
  ciaH Streptococcus pneumoniae TIGR4

49.676

100

0.501
  ciaH Streptococcus mutans UA159

49.89

99.129

0.495

Multiple sequence alignment